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Quizzes and Polls

Latest Quiz

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September 2016

Polycyclic Eruption of the Thighs

A young woman had a painful erythematous eruption over her thighs that was worse during winter but no other symptoms; she was a nonsmoker, took no medications, and worked at a horse stable and rode for many hours a day. What is your diagnosis?

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Test your knowledge with previous versions of the JAMA Dermatology Clinical Challenge.

August 2016

Painful Chronic Ulcers on the Neck and Back

A man in his 60s presented with low-grade fevers, unintentional 80-pound weight loss, productive cough, and development of cutaneous ulcers over a 6-month period.

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August 2016

Facial Erythematous Papules in a Young Woman

A woman in her 20s presented with multiple facial papules since childhood that progressively increased in number.

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August 2016

Ulcers of the Ventral Aspect of Fingers

A 42-year-old African American man presented with a 7-month history of fatigue, exertional dyspnea, arthralgias, hand swelling, tender ulcerations, hair loss, and a 50-pound weight loss; he presented with ulcers on his dorsal metacarpophalangeal joints. What is your diagnosis?

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August 2016

Clusters of Painful Blue Papules

A woman in her 30s had discrete clustered painful blue papules on her face and extremities; the lesions had been present since childhood, but the size and intensity of pain had recently increased. What is your diagnosis?

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August 2016

A Large Verrucous Plaque on the Calf

A man in his 20s presented with a large, verrucous plaque on his right calf; the lesion initially appeared as a small, bluish plaque at a young age and had gradually increased in size with subsequent development of wart-like features. What is your diagnosis?

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August 2016

Progressive Proliferation of Dark Papules in an African American Woman

An African American woman in her 30s with no medical history presented with a 4-year history of diffuse progressive proliferation of dark papules with first onset several weeks after a sunburn. What is your diagnosis?

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August 3, 2016

Longitudinal Erythronychia of the Fingernail

A man in his 70s presented with a split in the right fifth fingernail with paroxysmal, intermittent pain that was exacerbated by cold weather for the past 10 years.

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July 6, 2016

Hypopigmented Macules on the Face and Neck of a Man

A man in his 40s presented with a 2-year history of multiple asymptomatic hypopigmented macules on the face and neck with no hair growth at the site of the lesions. What is your diagnosis?

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June 8, 2016

Fixed Erythema on the Abdomen in a Hematologic Patient

A man in his 60s presented with a 2-month history of painful, occasionally pruritic, fixed erythema on the abdomen and a splenic marginal zone lymphoma with bone marrow infiltration. What is your diagnosis?

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June 1, 2016

Large Annular Plaque on the Arm of a Patient With Recurrent Headaches

A woman in her 50s had a 12-cm-wide, soft, nontender plaque with a raised, nodular, and slightly desquamative erythematoviolaceous border and a clear, atrophic center with an increase in wrinkle depth on her upper right arm. What is your diagnosis?

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May 25, 2016

Painful Cutaneous Nodule of the Jawline

A woman in her 30s presented with a 3-year history of painful nodules on her lower extremities, neck, and jawline; her medical history included seasonal allergies, and she did not take any prescription medications. What is your diagnosis?

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May 18, 2016

Folliculocentric and Octagonal Scaly Papules

A woman in her early 50s presented with a 1- to 2-year history of outbreaks of mildly pruritic “flowers” on her skin occurring in crops of 3 to 4 on arms, legs, trunk, and buttocks that would last a few months before spontaneously resolving without scarring. What is your diagnosis?

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April 27, 2016

Purple Crusted Nodules in a Patient With End-stage Liver Disease

A 32-year-old male with a history of end-stage liver disease secondary to alcoholic cirrhosis presented with a 2-week history of a skin rash that developed at a facility where he was being treated for hepatic encephalopathy; the lesions began on his face, spread to his thighs, and were mildly pruritic. What is your diagnosis?

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January 20, 2016

A Discordant Cutaneous Eruption in a Neonatal Twin

A male neonate born prematurely at 27 weeks’ gestational age had a erythematous eruption at birth, exhibiting 100 to 200 pink papules, 0.05 to 0.2 cm in size, distributed on the trunk, extensor upper arms, and upper legs. What is your diagnosis?

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January 13, 2016

Erythematous Plaques and Violaceous Nodules on Extensor Surfaces

A woman in her 60s presented with a 6-month history of itchy eruptions that initially started on the arms and then spread to involve the lower legs. The patient reported no fevers, fatigue, myalgias, arthritis, shortness of breath, oral ulcers, or recent infections. Punch biopsy showed neutrophilic infiltrate. What is your diagnosis?

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January 6, 2016

A Patient With Blue Ears

A 65-year-old woman presented with a 5-year history of increasing blue discoloration of her ears; she had mild knee arthralgia and was seeing an ophthalmologist annually regarding brown spots on both eyes diagnosed as conjunctival nevi.

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December 30, 2015

Necrotic and Ulcerated Plaques Over Face and Extremities

A man had ulceration of the soles, legs, hands, elbows, and face; numbness of the hands and feet; diffuse infiltration of the face and madarosis of the lateral half of the eyebrows; and hypoaesthesia over the palms, proximal forearms, feet, and legs.

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December 16, 2015

Bullae and Erosions on Sun-Exposed Skin

A man in his 60s with a history of acute myeloid leukemia, for which he had received an allogeneic stem cell transplant that was complicated by graft-vs-host disease, presented with new-onset bullae and erosions over sun-exposed areas and bony prominences.

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December 9, 2015

Immovable Ears

A man in his 70s had bilateral auricular rigidity, and a biopsy specimen showed regions of ossification and calcification.

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December 2, 2015

Linear Scars in a 4-Week-Old Girl

A 4-week-old girl who had erosions on the left leg, left side of the neck, abdomen, and left ear at birth presented with linear scars. Clinical examination revealed erythematous atrophic streaks along Blaschko lines and soft skin-colored papules on the left leg.

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November 25, 2015

Disseminated Red Violaceous Papulonodular Lesions

A woman in her 40s presented with a 6-month history of a generalized, asymptomatic eruption of red violaceous, nontender, rubbery nodules and papules together with brownish-red patches without enlargement of lymph nodes or hepatosplenomegaly.

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November 18, 2015

Localized Hair Repigmentation in a 91-Year-Old Woman

An elderly woman had a patch of black hair within otherwise gray hair, an irregularly pigmented, brownish patch on the underlying scalp skin, multiple seborrhoic keratoses, and a actinic keratosis.

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November 11, 2015

Ulcerative Pretibial Lesions and Immunosuppression

A man in his 50s with a kidney transplant was admitted for a 1-month history of an enlarging left lower extremity mass that ulcerated, was occasionally painful, and drained small amounts of sanguinopurulent fluid.

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November 4, 2015

Painful and Pruritic Papules in the Gray Shading of a Tattoo

A woman presented with multiple painful, pruritic papules and pustules that developed 1 week after the addition of gray shading toa tattoo; results from a routine wound culture were negative for organisms.

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October 28, 2015

Bruising and Hemorrhagic Vesicles on the Tongue

A woman in her 70s with recently diagnosed diastolic heart failure was admitted for worsening dyspnea and also reported easy bruising with minor trauma and erosions on the lateral tongue.

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October 14, 2015

Rapidly Growing, Painful Nodule on the Upper Cutaneous Lip

This quiz case describes a patient with a growing, painful nodule on the upper cutaneous lip and several smaller papules on the face and neck.

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September 23, 2015

Polycyclic Brownish to Reddish Macules on the Skin in an Infant

A 6-month-old daughter of nonconsanguineous parents was seen with multiple polycyclic dark to less dark brown, partly livid shimmering macules, which covered large areas of the back, neck, buttocks, and lower extremities. New lesions had appeared during the past weeks on the shoulders.

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September 9, 2015

Persistent, Nontender Lip Swelling in a Patient With HIV

A man in his early 40s with a history of verruca vulgaris, dyshidrotic eczema, and HIV presented with a chief complaint of dry, swollen lips, a 1-month history of “puffy and bumpy” lips, and a sometimes “dry and scaly” lower lip but no bleeding.

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September 2, 2015

Blistering Eruption of the Buttocks

An elderly woman with progressive, painful blisters, ulcers of the groin, and enlargement of the tongue was found to have circinate purpuric patches with erosions on the natal cleft and buttocks.

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August 26, 2015

Chronic Nonhealing Ulcerated Nodules in a Spanish Boy After Traveling

A 12-year-old boy presents with a 3-month history of ulcerated lesions on the dorsal aspect of his feet after traveling.

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August 19, 2015

Sandpapery Skin

A woman in her 70s presented with rough sandpapery skin that had been present for 2.5 years.

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August 12, 2015

Pruritic, Pink Scaling Plaques on the Face and Trunk

A woman in her 40s with a medical history of pulmonary embolism and deep venous thrombosis presented with a 6-month history of pruritic, pink scaling plaques on her face and neck with subsequent lesions on the chest, abdomen, and back that flared with sun exposure.

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August 5, 2015

Violaceous Eruption on the Head and Extremities

A man in his 50s of Indian descent presented with a pruritic eruption on his scalp, arms, neck, and feet.

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July 29, 2015

Unilateral Stellate Purpura of the Ankle

This case report of a woman with unilateral stellate purpura of the ankle reveals how a complete skin examination is critical for diagnostic and prognostic purposes.

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June 17, 2015

Immediate Pigmentation After Laser Treatment


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June 10, 2015

Asymptomatic Papular Eruption in a Teenage Boy


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May 13, 2015

Creamy Yellow Concretions in Axillary Hair


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April 29, 2015

Axillary Acne Agminata


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April 8, 2015

Ulcerated Plaque With Lymphocutaneous Spread

This case study describes a woman with an ulcerated plaque on the forearm after a hospital admission for congestive heart failure. Histopathologic examination of a 4-mm punch biopsy specimen demonstrated marked superficial and deep inflammation composed predominantly of neutrophils with associated tissue necrosis.

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April 1, 2015

Erythematous Papules on the Forearms

This case report describes a 72-year-old man with heart disease and a 2-month history of scaly erythematous papules on both forearms that did not improve with chlorhexidine or hydrocortisone. He had elevated creatinine and serum iodine but was otherwise asymptomatic.

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March 11, 2015

Erythematous Papules and Vesicles on the Palms, Soles, and Oropharynx

A 23-year-old white man who has sex with men (MSM) presented with a 1-month history of skin lesions on the palms and soles as well as a 2-week history of lesions in his oropharynx.

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February 11, 2015

Conflicting Dermoscopic Criteria in a Suspicious Lesion

A man in his 30s with no medical history of illness presented with a lesion of concern on his left scalp.

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January 21, 2015

Polymorphic Blistering Eruption and Stomatitis in a Patient With Non-Hodgkin Lymphoma

A man in his 70s with a history of T2N2 melanoma, locally metastatic squamous cell carcinoma, and non-Hodgkin follicular lymphoma presented with weakness, a blistering erythematous eruption, and painful oral lesions of 1 month's duration.

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November 19, 2014

Tense Bullae on the Palms and Soles

A man in his 70s presented with a 2-week history of a bullous eruption localized to the hands and feet. He denied having pruritus or spontaneous bleeding but reported discomfort from the pressure of intact bullae.

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November 5, 2014

A Purpuric Patch on the Flank

A man in his 60s presented to the emergency department for left flank pain of 1 week’s duration. His medical history included severe peripheral arterial disease and a remote history of ruptured abdominal aortic aneurysm.

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September 29, 2014

Tender Leg Nodules in a Hospitalized Patient

A man in his 60s was admitted to the hospital for an 8-day history of abdominal pain, bloating, vomiting, diarrhea, subjective fever, weight loss, and fatigue.

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Test your knowledge with previous versions of the JAMA Dermatology Clinical Challenge Quizzes.

February 2013

Eruption in a Patient With Crohn Disease

A 54-year-old woman presented with a 2-year history of a mildly pruritic, golden-brown rash that first developed on her palms and progressed to her shins and soles.

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January 2013

Eruption in a Patient With Crohn Disease

A 53-year-old white man presented with an acute onset of inflammatory papulopustules on the central part of his face and head and a few lesions on his trunk that fused and discharged purulent material.

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December 2012

Violaceous and Ulcerated Plaque Following a Cesarean Section

A 27-year-old woman with a painful, reddish-blue (livedoid) skin area showing small ulcerations on the lower abdomen was examined.

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November 2012

Diffuse Skin Thickening and Linear Papules in a 59-Year-Old Woman

A 59-year-old woman presented with a 4-month history of diffuse skin thickening with overlying linear papules. She reported associated dyspnea, muscle weakness, fatigue, decreased acral range of motion, and decreased oral aperture.

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October 2012

Pustules and Sinus Tracts Involving the Right Arm of an Elderly Patient

An 83-year-old man with a history of diabetes and chronic obstructive pulmonary disorder (taking prednisone, 5 mg/d) was admitted to our facility with a month-long history of persistent right arm swelling, erythema, and pain.

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September 2012

Soft Subcutaneous Plantar Masses

A 3-year-old boy presented with asymptomatic growths on both feet that his parents had noticed 1 year prior.

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August 2012

A Growing Pigmented Lesion in a Child With a History of Bone Marrow Transplant and Irradiation

A 14-year-old Hispanic female with a history of aplastic anemia requiring 2 bone marrow transplants presented with a 4-month history of a 6-mm brown-black papule in her left lower abdomen.

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July 2012

Numerous Skin-Colored Papules on the Face and Neck

A 36-year-old woman presented with a 9-month history of numerous small skin-colored papules scattered over her lateral cheeks, forehead, and neck.

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June 2012

Vesicular Lesions on the Vulva

A 45-year-old woman presented with a 5-year history of pruritic, exudative lesions in the vulvar area.

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May 2012

Lentigolike Macules and Erythematous Plaques on Trunk and Extremities

A 60-year-old woman presented with an 8-year history of an asymptomatic progressive skin eruption on the trunk and extremities.

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April 2012

Multiple Brown Macules and Papules on a Female Teenager

A 14-year-old Hispanic girl presented with a 1-year history of multiple asymptomatic hyperpigmented macules and papules over her arms, legs, trunk, and face.

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March 2012

Ulcers and Stellate Scars on Bilateral Ankles

A 75-year-old woman presented with a 2-year history of exquisitely tender ulcerations on her bilateral ankles, which caused pain with ambulation. She had a history of multiple miscarriages, a myocardial infarction at age 60 years, and hypertension.

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February 2012

Hyperpigmented Asymptomatic Macule in a Fingertip With Suspicious Dermoscopic Pattern

A previously healthy 51-year-old man presented with asymptomatic brown-pigmented lesions on his first left-hand fingertip. The lesions had appeared 3 months ago and gradually spread. He had no history of tobacco smoking, wearing rings, chemotherapy, or work involving friction or in wet places.

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