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Observation | June 12, 2013 
Lip Abscess Associated With Isotretinoin Treatment of Acne Vulgaris
Kevin C. Huoh, MD; Kay W. Chang, MD
ImportanceImportance Isotretinoin is frequently prescribed for the treatment of acne vulgaris. Among the numerous documented adverse effects, most common are xerostomia and ...
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JAMA Dermatol. Published online June 12, 2013. doi:10.1001/jamadermatol.2013.4066
Observation | June 12, 2013 
Primary Cutaneous CD4+ Small- to Medium-Sized Pleomorphic T-cell Lymphoma:  Temporary Remission by Oral Doxycycline
Ferdinand Toberer, MD; Wolfgang Hartschuh, MD; Eva Hadaschik, MD
ImportanceImportance In the recent World Health Organization–European Organisation for Research and Treatment of Cancer classification, primary cutaneous CD4+ small- to medium-sized pleomorphic ...
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JAMA Dermatol. Published online June 12, 2013. doi:10.1001/jamadermatol.2013.4162
Study | June 12, 2013 
Atypical (Dysplastic) Nevi:  Outcomes of Surgical Excision and Association With Melanoma
Kavitha K. Reddy, MD; Michele J. Farber, MD; Jag Bhawan, MD; Roy G. Geronemus, MD; Gary S. Rogers, MD
ObjectiveObjective To evaluate the effect of surgical excision, performed after biopsy diagnosis of dysplastic nevus, on final diagnosis, melanoma prevention, and melanoma ...
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JAMA Dermatol. Published online June 12, 2013. doi:10.1001/jamadermatol.2013.4440
Practice Gaps | June 12, 2013 
Immediate Curettage and Electrodessication Following Biopsy of Suspected Basal Cell Carcinoma at Initial Visit
Fiona Zwald, MD
This retrospective medical chart review attempts to establish the clinical value of performing a biopsy and treating a lesion suspected to be ...
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JAMA Dermatol. Published online June 12, 2013. doi:10.1001/jamadermatol.2013.4463
Observation | June 12, 2013 
Intralesional Sodium Thiosulfate for the Treatment of Calciphylaxis
Lauren Strazzula, BA; Sagar U. Nigwekar, MD; David Steele, MD; William Tsiaras, MD, PhD; Meghan Sise, MD; Sabina Bis, MD; Gideon P. Smith, MD, PhD; Daniela Kroshinsky, MD, MPH
ImportanceImportance Calciphylaxis is a potentially fatal disorder of abnormal calcium deposition. Patients commonly present with painful retiform to stellate purpuric lesions that ...
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JAMA Dermatol. Published online June 12, 2013. doi:10.1001/jamadermatol.2013.4565
Off-Center Fold | June 12, 2013 
Rapidly Enlarging Nodule on the Scalp—Quiz Case
Whitney Pollard, DO; James Pehoushek, MD, MPH
JAMA Dermatol. Published online June 12, 2013. doi:10.1001/jamadermatol.2013.67a
Off-Center Fold | June 12, 2013 
Rapidly Enlarging Nodule on the Scalp—Diagnosis
JAMA Dermatol. Published online June 12, 2013. doi:10.1001/jamadermatol.2013.67b
Research Letters | June 12, 2013 
Biopsy Followed by Immediate Curettage and Electrodesiccation of Suspected Basal Cell Carcinomas at the First Visit
Gary M. White, MD; Hui Cynthia Zhou, MS, PhD; Raoul J. Burchette, MS
The diagnosis and treatment of basal cell carcinoma (BCC) represents a significant portion of the work for many dermatologists. Any efficiency in ...
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JAMA Dermatol. Published online June 12, 2013. doi:10.1001/jamadermatol.2013.727
Observation | June 5, 2013 
Dermoscopy and Confocal Microscopy of Nested Melanoma of the Elderly:  Recognizing a Newly Defined Entity
Caterina Longo, MD; Iris Zalaudek, MD; Simonetta Piana, MD; Giovanni Pellacani, MD; Aimilios Lallas, MD; Camilla Reggiani, MD; Giuseppe Argenziano, MD
ImportanceImportance Nested melanoma of the elderly is a newly identified histopathologic variant of superficial spreading melanoma, characterized by intraepidermal large nests. However, ...
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JAMA Dermatol. Published online June 05, 2013. doi:10.1001/jamadermatol.2013.321
Off-Center Fold | June 5, 2013 
Scleroderma-Like Hands in a 16-Year-Old Boy—Quiz Case
Meena Arunachalam, MD; Andrea Bassi, MD; Massimiliano Galeone, MD; Federica Scarfi, MD; Elisa Difonzo, MD
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JAMA Dermatol. Published online June 05, 2013. doi:10.1001/jamadermatol.2013.3370a
Off-Center Fold | June 5, 2013 
Scleroderma-Like Hands in a 16-Year-Old Boy—Diagnosis
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JAMA Dermatol. Published online June 05, 2013. doi:10.1001/jamadermatol.2013.3370b
Research Letters | June 5, 2013 
Association Between Vitiligo and Atopic Disorders: A Pilot Study
Jonathan I. Silverberg, MD, PhD, MPH; Nanette B. Silverberg, MD
Includes: Supplemental Content
Vitiligo is an autoimmune disorder characterized by melanocyte destruction and loss of pigmentation. Vitiligo has a higher prevalence of autoimmune disorders.1 Little ...
JAMA Dermatol. Published online June 05, 2013. doi:10.1001/jamadermatol.2013.4228
Research Letters | June 5, 2013 
A Randomized, Double-Blinded, Placebo-Controlled Trial of Oral Polypodium leucotomos Extract as an Adjunct to Sunscreen in the Treatment of Melasma
Ammar M. Ahmed, MD; Isha Lopez, MD; Francisco Perese, BS; Rebecca Vasquez, MD; Linda S. Hynan, PhD; Benjamin Chong, MD; Amit G. Pandya, MD
Treatments for melasma include photoprotection in conjunction with topical agents such as hydroquinone, retinoids, or combinations. These regimens, while reasonably effective, are ...
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JAMA Dermatol. Published online June 05, 2013. doi:10.1001/jamadermatol.2013.4294
Editorial | June 5, 2013 
Nested Melanoma, A Newly Defined Entity
Claus Garbe, MD; Gisela Metzler, MD
Three cases of nested melanoma have been documented in detail by Longo and colleagues.1 Clinically, we see flat, asymmetrically shaped lesions with ...
JAMA Dermatol. Published online June 05, 2013. doi:10.1001/jamadermatol.2013.4305
Correspondence | June 5, 2013 
Pigmented Basal Cell Carcinoma:  Uncommon Presentation in Blue-Eyed Patients
Casey I. Coleman, BS; Lara Wine-Lee, MD, PhD; William D. James, MD
While other subtypes of basal cell carcinoma (BCC) primarily affect individuals with light eyes and hair, fair complexion, and an inability to ...
JAMA Dermatol. Published online June 05, 2013. doi:10.1001/jamadermatol.2013.491
Practice Gaps | May 29, 2013 
Gaining Insights Into the Relationship of Obesity, Weight Loss, and Psoriasis:  Comment on “Effect of Weight Loss on the Severity of Psoriasis: A Randomized Clinical Study”
Michael L. Shelling, MD; Robert S. Kirsner, MD, PhD
Dermatologists now recognize that patients with psoriasis have an associated increased risk for and prevalence of hypertension, diabetes, dyslipidemia, obesity, and vascular ...
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JAMA Dermatol. Published online May 29, 2013. doi:10.1001/jamadermatol.2013.3383
Editorial | May 29, 2013 
Psoriasis and the Obesity Epidemic:  The Effect of Weight Loss
Michael T. Caglia, MD; Gerald G. Krueger, MD
Man's desire to control chronic disease inevitably turns to how diet could effect the disease state; we would purport that this notion ...
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JAMA Dermatol. Published online May 29, 2013. doi:10.1001/jamadermatol.2013.4512
Study | May 29, 2013 
Effect of Weight Loss on the Severity of Psoriasis:  A Randomized Clinical Study
Peter Jensen, MD, PhD; Claus Zachariae, MD, DMSc; Robin Christensen, MSc, PhD; Nina R. W. Geiker, MSc; Bente K. Schaadt, MD, PhD; Steen Stender, MD, DMSc; Peter R. Hansen, MD, DMSc; Arne Astrup, MD, DMSc; Lone Skov, MD, DMSc
ImportanceImportance Psoriasis is associated with adiposity and weight gain increases the severity of psoriasis and the risk of incident psoriasis. Therefore, we ...
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JAMA Dermatol. Published online May 29, 2013. doi:10.1001/jamadermatol.2013.722
Off-Center Fold | May 29, 2013 
Long-Standing Filiform, Blaschkoid Papules—Quiz Case
Ellen Koch, MD; Luke Johnson, BS; Robin Gehris, MD
JAMA Dermatol. Published online May 29, 2013. doi:10.1001/jamadermatol.2013.87a
Off-Center Fold | May 29, 2013 
Long-Standing Filiform, Blaschkoid Papules—Diagnosis
JAMA Dermatol. Published online May 29, 2013. doi:10.1001/jamadermatol.2013.87b

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