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 Showing 1-20 of 60 Articles
Original Investigation  FREE
Ellen N. Pritchett, MD, MPH; Alden Doyle, MD, MPH; Christine M. Shaver, MD; Brett Miller, MD; Mark Abdelmalek, MD; Carrie Ann Cusack, MD; Gregory E. Malat, PharmD; Christina Lee Chung, MD

Importance  Organ transplant recipients have a higher incidence of skin cancer. This risk is magnified over time and with continued exposure to immunosuppression. Skin cancer in nonwhite patients is associated with greater morbidity and mortality owing to diagnosis at a more advanced stage, which suggests that nonwhite ...

JAMA Dermatology Clinicopathological Challenge 
Julia Wu, MD; Rebecca Baxt, MD, MBA; Mark Jacobson, MD

A young woman had a painful erythematous eruption over her thighs that was worse during winter but no other symptoms; she was a nonsmoker, took no medications, and worked at a horse stable and rode for many hours a day. What is your diagnosis?

Research Letter  FREE
Vinayak K. Nahar, MD, MS, PhD; Meagen Rosenthal, PhD; Stephenie C. Lemon, PhD; Dawn M. Holman, MPH; Meg Watson, MPH; Joel J. Hillhouse, PhD; Sherry L. Pagoto, PhD

This survey study evaluates the tanning practices, reasons for tanning, and association with tanning addiction of adults who use tanning beds in private residences.

Belen Rubio-Gonzalez, MD; Jasmine Zain, MD; Lino Garcia, MS; Steven T. Rosen, MD; Christiane Querfeld, MD, PhD

This case report describes a case of cutaneous gamma-delta T-cell lymphoma successfully treated with brentuximab vedotin.

Original Investigation 
Audrey A. Jacobsen, BA; Ana Galvan, BS; Claudina Canaan Lachapelle, MD; Cheryl B. Wohl, MPH; Robert S. Kirsner, MD, PhD; John Strasswimmer, MD, PhD

Importance  As the minority population increases in the United States, the incidence of skin cancer has important public health consequences, including poor skin cancer outcomes, in part because of late-stage diagnosis. Therefore, it is important to identify obstacles in skin cancer prevention in these communities.

Objective  ...

JAMA Dermatology Clinicopathological Challenge 
Emily M. Erstine, MD, MBA; Angela M. B. Collie, MD, PhD; Melissa P. Piliang, MD

A man in his 60s presented with low-grade fevers, unintentional 80-pound weight loss, productive cough, and development of cutaneous ulcers over a 6-month period. What is your diagnosis?

Research Letter 
Mary E. Logue, BA; Tyler Hough, BS; Yuridia Leyva, MS; Jaron Kee, BS; Marianne Berwick, PhD, MPH

This study surveys Southwestern American Indian and non-Hispanic white individuals in New Mexico regarding sun-protective behaviors.

Michael A. Cardis, MD; Helena B. Pasieka, MD, MS

This case report describes the occurrence of adverse effects after application of topical neuromodulators for the treatment of pruritus.

Original Investigation 
Euphemia W. Mu, MD; Jesse M. Lewin, MD; Mary L. Stevenson, MD; Shane A. Meehan, MD; John A. Carucci, MD, PhD; Daniel S. Gareau, PhD, MCR
Includes: Supplemental Content

Importance  Confocal microscopy has the potential to provide rapid bedside pathologic analysis, but clinical adoption has been limited in part by the need for physician retraining to interpret grayscale images. Digitally stained confocal mosaics (DSCMs) mimic the colors of routine histologic specimens and may increase adaptability of ...

JAMA Dermatology Clinicopathological Challenge 
Jihane Abou Rahal, MD; Olivier Cogrel, MD; Bernard Cribier, MD, PhD

A woman in her 20s presented with multiple facial papules since childhood that progressively increased in number. What is your diagnosis?

Research Letter 
Matan Rothschild, MD; Greg Duhon, MD; Rashid Riaz, MD; Vybhav Jetty, MD; Naila Goldenberg, MD; Charles J. Glueck, MD; Ping Wang, PhD

This case series describes palmar crease xanthomas and other dermatologic manifestations of familial dysbetalipoproteinemia and mutant apoE2/2 genotype.

Warren R. Heymann, MD

This case report describes a case of a dermatologic cyst interpreted as an airport security threat.

Viewpoint  FREE
Gery P. Guy Jr, PhD, MPH; Dawn M. Holman, MPH; Meg Watson, MPH

This Viewpoint discusses the important role of schools in the prevention of skin cancer.

To make a definitive diagnosis of skin cancer, dermatologists have been required to obtain skin biopsy specimens of suspicious lesions and to examine tissue pathologic abnormalities ex vivo under light microscopy. In the past decades, high diagnostic sensitivity, which is associated with a low biopsy threshold,1 has ...

Original Investigation 
Stefania Borsari, MD; Riccardo Pampena, MD; Aimilios Lallas, MD; Athanassios Kyrgidis, MD; Elvira Moscarella, MD; Elisa Benati, MD; Margherita Raucci, ARNP; Giovanni Pellacani, MD; Iris Zalaudek, MD; Giuseppe Argenziano, MD; Caterina Longo, MD, PhD
Includes: Supplemental Content

Importance  Reflectance confocal microscopy (RCM) improves diagnostic accuracy in skin cancer detection when combined with dermoscopy; however, little evidence has been gathered regarding its real impact on routine clinical workflow, and, to our knowledge, no studies have defined the terms for its optimal application.

Objective  To ...

Original Investigation 
Thaís Corsetti Grazziotin, MD, PhD; Ivette Alarcon, MD; Renan Rangel Bonamigo, MD, PhD; Cristina Carrera, MD, PhD; Miriam Potrony, PhD; Paula Aguilera, MD, PhD; Joan-Anton Puig-Butillé, PhD; Johanna Brito, MD; Celia Badenas, PhD; Llúcia Alós, MD; Josep Malvehy, MD, PhD; Susana Puig, MD, PhD
Includes: Supplemental Content

Importance  The improved knowledge of clinical, morphologic, and epidemiologic heterogeneity of melanoma in the context of multiple primary and familial melanomas may improve prevention, diagnosis, and prognosis of melanoma.

Objective  To characterize reflectance confocal microscopy (RCM) morphologic patterns of melanomas in multiple primary and familial melanomas....

JAMA Dermatology Clinicopathological Challenge 
Sungat K. Grewal, BS; Chris T. Derk, MD, MS; Misha Rosenbach, MD

A 42-year-old African American man presented with a 7-month history of fatigue, exertional dyspnea, arthralgias, hand swelling, tender ulcerations, hair loss, and a 50-pound weight loss; he presented with ulcers on his dorsal metacarpophalangeal joints. What is your diagnosis?

Mehdi Rashighi, MD; John E. Harris, MD, PhD

In this issue of JAMA Dermatology, Speeckaert and colleagues1 report that levels of the soluble CD25 and CD27 molecules (sCD25 and sCD27) are elevated in the serum of patients with active vitiligo compared with patients with stable disease. In addition, sCD25 levels were found to be ...

Original Investigation 
Reinhart Speeckaert, MD, PhD; Jo Lambert, MD, PhD; Nanja van Geel, MD, PhD

Importance  It is difficult to determine disease activity in vitiligo owing to the absence of inflammatory signs, such as erythema or scaling. A biomarker that could confirm active disease and indicate likely future disease progression would therefore be of considerable value.

Objective  To investigate whether soluble ...

Original Investigation 
Bobbak Mansouri, MD; Dario Kivelevitch, MD; Balaji Natarajan, MD; Aditya A. Joshi, MD; Caitriona Ryan, MD; Katie Benjegerdes, BS; Jeffrey M. Schussler, MD; Daniel J. Rader, MD; Muredach P. Reilly, MBBCH, MSCE; Alan Menter, MD; Nehal N. Mehta, MD, MSCE
Includes: Supplemental Content

Importance  Psoriasis is associated with an increased risk of cardiovascular diseases. Subclinical atherosclerosis in patients with psoriasis has not been compared with other conditions associated with increased cardiovascular risk and more rigorous cardiovascular disease screening, such as type 2 diabetes.

Objective  To assess the burden of ...

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