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 Showing 1-20 of 81 Articles
Lola V. Stamm, PhD

This Viewpoint highlights the importance of screening refugees from leishmaniasis-endemic areas to prevent the spread of this disease.

This Viewpoint highlights that studies using unvalidated surrogate end points has led to the availability of many new anticancer drugs and that adopting similar standards for drugs aimed at nonlethal diseases might produce more drugs for these conditions.

Dane Hill, MD; Steven R. Feldman, MD, PhD

This is the best time to be alive in human history. Technology has objectively improved our lives in countless ways. In dermatology, this is perhaps best exemplified by the treatments we now have for psoriasis. Just a few years ago, we would have been ecstatic for a cyclosporine-like ...

Original Investigation  FREE
Miranda E. Rosenberg, BA; Steven P. Rosenberg, MD

Importance  Physicians from many specialties as well as primary care prescribe dermatologic medications; as insurance formularies become increasingly restrictive and more patients are covered with high-deductible insurance plans, many patients are forced to pay high retail prices to obtain their medications.

Objectives  To determine the changes ...

Original Investigation 
Robert J. Smith, BS; Jules B. Lipoff, MD

Importance  Patient satisfaction is an increasingly important component of health care quality measures. Online reviews of physicians represent a promising platform for capturing patient perspectives of care.

Objective  To identify qualitative themes associated with patient reviews of dermatologic care on consumer reporting websites.

Design, Setting, and ...

Editorial: Online Reviews of Physicians; Dane Hill, MD; Steven R. Feldman, MD, PhD
JAMA Dermatology Clinicopathological Challenge 
Rosario Alarcón-Cabrera, MD; Felipe Partarrieu-Mejías, BS; Fernanda Pérez-Velásquez, BS

A woman in her 40s presented with a 6-month history of a generalized, asymptomatic eruption of red violaceous, nontender, rubbery nodules and papules together with brownish-red patches without enlargement of lymph nodes or hepatosplenomegaly. What is your diagnosis?

Research Letter 
Gordon Bae, BA; Mengting Qiu; Erin Reese, MPH; Vinod Nambudiri, MD, MBA; Susan Huang, MD

This Research Letter analyzes sex and ethnicity trends among dermatology residents and compares them with other specialties and medical school graduates over multiple decades, highlighting the need for greater ethnic diversity among dermatologists.

Aurélie Marti, MS; Antoine Fauconneau, MD; Nora Ouhabrache, MD; Marie Beylot-Barry, MD, PhD; Anne Pham-Ledard, MD, PhD

This case report describes complete remission of squamous cell carcinoma after treatment with panitumumab in patient with cetuximab-induced anaphylaxis.

Original Investigation 
Murad Alam, MD, MSCI; Misbah Khan, MD; Emir Veledar, PhD; Marisa Pongprutthipan, MD; Arthur Flores, MD, PA; Meghan Dubina, MD; Michael Nodzenski, MS; Simon S. Yoo, MD

Importance  During Mohs micrographic surgery of nonmelanoma skin cancer (NMSC), inflammation in histologic frozen sections has been found to occasionally presage the detection of tumors in frozen sections of adjacent excision specimens.

Objective  To quantify the correlation between the location of inflammation without visible tumor in ...

Original Investigation 
Vassiliki Tzanetakou, MD; Theodora Kanni, MD; Sophia Giatrakou, MD; Alexandros Katoulis, MD, PhD; Evangelia Papadavid, MD, PhD; Mihai G. Netea, MD, PhD; Charles A. Dinarello, MD, PhD; Jos W. M. van der Meer, MD, PhD; Dimitrios Rigopoulos, MD, PhD; Evangelos J. Giamarellos-Bourboulis, MD, PhD
Includes: Supplemental Content

Importance  Hidradenitis suppurativa (HS) is a common skin disorder in which excessive inflammation is believed to have an important role. There is no specific therapy for HS.

Objective  To investigate the safety and efficacy of the anti-inflammatory biological therapy anakinra in HS.

Design, Setting, and Participants...

JAMA Dermatology Clinicopathological Challenge 
Valerie C. Amann, MD; Reinhard Dummer, MD

An elderly woman had a patch of black hair within otherwise gray hair, an irregularly pigmented, brownish patch on the underlying scalp skin, multiple seborrhoic keratoses, and a actinic keratosis. What is your diagnosis?

Research Letter 
Chloé Sachs; Dan Lipsker, MD, PhD

This study describes vascular lesions in patients with tuberous sclerosis complex, which could be minor cutaneous markers of the disease.

Suzanne J. Tintle, MD, MPH; Julie C. Harper, MD; Guy F. Webster, MD, PhD; Grace K. Kim, DO; Diane M. Thiboutot, MD

This report of cases describes the safe and successful use of therapeutic-dose oral isotretinoin in 3 patients with a history of pseudotumor cerebri.

Elena Thomaidou, MD; Avital Nahmias, MD; Leon Gilead, MD; Abraham Zlotogorski, MD; Yuval Ramot, MD

This case report describes the rapid clearance of necrolytic migratory erythema following intravenous administration of amino acids.

Original Investigation 
Daniel B. Horton, MD, MSCE; Frank I. Scott, MD, MSCE; Kevin Haynes, PharmD, MSCE; Mary E. Putt, PhD, ScD; Carlos D. Rose, MD, CIP; James D. Lewis, MD, MSCE; Brian L. Strom, MD, MPH
Includes: Supplemental Content

Importance  Antibiotics disrupt human microbiota and have been associated with several pediatric autoimmune diseases. Psoriasis activity has been linked to group A streptococcal and viral infections.

Objective  To determine whether antibiotic exposure and infections are independently associated with incident psoriasis in children.

Design, Setting, and Participants...

Original Investigation 
Rui Xu, BS; Mu-Yan Cai, MD; Rong-Zhen Luo, MD; Xin Tian, MD; Jian-de Han, MD; Mu-Kai Chen, MD

Importance  The CD133 protein has been considered a key biomarker of cancer stem cells in various cancers. However, the expression status and prognostic significance of CD133 in cutaneous squamous cell carcinoma (cSCC) are poorly understood.

Objective  To investigate the expression of cancer stem cell biomarker CD133 ...

JAMA Dermatology Clinicopathological Challenge 
Patricia M. Richey, BS; Arash Radfar, MD, PhD; Ali A. Damavandy, MD

A man in his 50s with a kidney transplant was admitted for a 1-month history of an enlarging left lower extremity mass that ulcerated, was occasionally painful, and drained small amounts of sanguinopurulent fluid. What is your diagnosis?

Research Letter 
Natalie A. Wright, MD; Daniel R. Mazori, BA; Mital Patel, MD; Joseph F. Merola, MD, MMSC; Alisa N. Femia, MD; Ruth Ann Vleugels, MD, MPH

This study reports that misdiagnoses, unnecessary procedures, and undertreatment were common among patients with eosinophilic fasciitis, while combination therapy with corticosteroids and methotrexate resulted in higher rates of complete response.

Research Letter 
Kareem Halim, MD; Qing Yu Weng, BS; Ifedayo Kuye, BA; Cara Joyce, PhD; Arash Mostaghimi, MD, MPA

This review of medical records assesses the use of health care resources and costs associated with dermatology nonattendance in patients at university-affiliated dermatology clinics.

Rachel M. Cymerman, BA; David E. Cohen, MD

This case report describes the successful treatment of acrodermatitis continua of Hallopeau with ustekinumab as monotherapy.

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