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 Showing 1-20 of 92 Articles
Case Report/Case Series 
Saskia Ingen-Housz-Oro, MD; Laurence Valeyrie-Allanore, MD; Anne Cosnes, MD; Nicolas Ortonne, MD, PhD; Sophie Hüe, MD, PhD; Muriel Paul, PhD; Pierre Wolkenstein, MD, PhD; Olivier Chosidow, MD, PhD

Importance  The main component of the first-line treatment of pemphigus vulgaris is high doses of systemic corticosteroids, but adverse effects of these drugs are frequent and sometimes severe. Rituximab has shown effectiveness as a corticosteroid-sparing agent or in case of relapse. To our knowledge, the effectiveness of ...

Research Letter 
Kimberly A. Mallett, PhD; Sarah Ackerman, MS; Rob Turrisi, PhD; June K. Robinson, MD
The association between excessive UV light (UVL) exposure and skin cancer is well documented.1 Therefore, it is essential that individuals with a history of skin cancer or other risk factors are able to successfully implement precautions to protect their skin. While studies show that many dermatology patients, particularly those who ...
Topics: dermatology; sunburn
Research Letter 
Oluwatobi A. Ogbechie, BA; Vinod E. Nambudiri, MD, MBA; Ruth Ann Vleugels, MD, MPH
The implementation of the Patient Protection and Affordable Care Act has renewed interest in the appropriate use and delivery of specialty services.1 Teledermatology has been touted as a potential solution to improve access, particularly in the context of the impending dermatology workforce shortage.2 While studies have demonstrated that teledermatology may ...
Observation 
Amit K. Malhotra, MD; Jerzy A. Lis, PhD; M. Ramam, MD
Insects can cause a variety of dermatologic problems usually presenting with inflammatory skin lesions. Cydnidae insects (family, Cydnidae; order, Hemiptera; suborder, Heteroptera; superfamily, Pentatomoidea), also known as burrowing (or burrower) bugs, are uncommon in urban areas and usually considered harmless to humans, though there have been anecdotal reports of the ...
JAMA Dermatology Clinicopathological Challenge 
Darlene E. Gou, BS, MS; Jake E. Turrentine, MD; Kiran Motaparthi, MD
Original Investigation 
Nitin Garg, MD; Jonathan I. Silverberg, MD, PhD, MPH
Includes: Supplemental Content

Importance  Adults with eczema have multiple risk factors for accidental injury. However, little is known about the risk of injury in adult patients with eczema.

Objective  To determine whether adult eczema is associated with an increased risk of injury.

Design, Setting, and Participants  A prospective ...

Original Investigation 
Sherry L. Pagoto, PhD; Stephenie C. Lemon, PhD; Jessica L. Oleski, MA; Jonathan M. Scully, BA; Gin-Fei Olendzki, MS; Martinus M. Evans, BS; Wenjun Li, PhD; L. Carter Florence, MPH; Brittany Kirkland, BS; Joel J. Hillhouse, PhD

Importance  Indoor tanning is widespread among young adults in the United States despite evidence establishing it as a risk factor for skin cancer. The availability of tanning salons on or near college campuses has not been formally evaluated.

Objective  To evaluate the availability of indoor tanning ...

Original Investigation 
Jack S. Resneck Jr, MD; Aaron Quiggle, BA, MS; Michael Liu, BS; David W. Brewster, BA

Importance  Insurers are increasingly deploying “narrow networks” with fewer contracted physicians both in health plans offered in new state exchanges under the Affordable Care Act and in Medicare Advantage (MA) plans, which are commercial alternatives offered to Medicare beneficiaries. Patients choosing health plans rely on the accuracy ...

Case Report/Case Series 
Carrie Ann Cusack, MD; Rohit Nijhawan, MD; Brett Miller, MD; Mira Henien, BS; Gregory Malat, PharmD; Alden Doyle, MD; Mark Abdelmalek, MD

Importance  Immunosuppressed patients with solid organ transplants have an increased risk for nonmelanoma skin cancer. Vismodegib has been reported to be effective for select locally advanced or metastatic basal cell carcinomas. However, there is no data documenting the use and safety of vismodegib in immunosuppressed organ transplant ...

Research Letter 
Michael T. Cosulich, MD; Matthew A. Molenda, MD; Eliot Mostow, MD, MPH; Ashish C. Bhatia, MD; Robert T. Brodell, MD
Lipomas are benign proliferations of mature fat that are occasionally tender. Common treatment approaches include elliptical excision, liposuction, and injection lipolysis. For most lipomas, we favor the minimal incision or “squeeze” technique, whereby lipomas are expressed through a small scalpel or punch incision.1,2 To our knowledge, the utilization rate of ...
Topics: lipoma
Research Letter 
Jennifer L. Hay, PhD; Mallorie Gordon, MA; Yuelin Li, PhD
First-degree relatives (FDRs) of patients with melanoma may be among the first to seek melanoma genetic risk information.1 Testing may subsequently prompt useful discussions regarding melanoma risk, early detection, and prevention with multiple family members. To explore this potential, this study examined the intended discussions of FDRs of patients with ...
Observation 
Cristina Thomas, BA; Pedram Yazdan, MD; Jonathan A. Cotliar, MD
We report a case of adult staphylococcal scalded skin syndrome (SSSS) superimposed on acute graft-vs-host disease (GVHD) and discuss the unique histologic features of both conditions seen on skin biopsy.
Observation 
Peiqi Su, MBBS (UK, Imperial College), MRCP(UK); Taige Cao, MBBS; Mark B. Y. Tang, MBBS, FRCP, FAMS; Hong Liang Tey, MBBS, MRCP(UK)
Optical coherence tomography (OCT) is a noninvasive imaging technique that allows real-time high-definition cross-sectional visualization of tissues. Conventional OCT was introduced in dermatology in 1997 and has shown benefit in evaluating malignant neoplasms and inflammatory skin disorders.1,2 High-definition OCT (HD-OCT) scanners have recently been developed; they provide a higher resolution ...
JAMA Dermatology Clinicopathological Challenge 
Corinne Atty, DO; Victoria M. Alagiozian-Angelova, MD; Areta Kowal-Vern, MD
Topics: dermatology; burns
Original Investigation  FREE
April W. Armstrong, MD, MPH; Mary Ann Johnson, MD; Steven Lin, MD; Emanual Maverakis, MD; Nasim Fazel, MD, DDS; Fu-Tong Liu, MD, PhD

Importance  New models of health care delivery for dermatological care have the potential to increase access and improve patient-centered outcomes.

Objective  To compare effectiveness of a direct-access, online model for follow-up dermatologic care in pediatric and adult patients with atopic dermatitis with that of in-person office ...

Case Report/Case Series 
Shirwa Sheik Ali, BSc; Allison L. Goddard, MD; Jason J. Luke, MD; Hilary Donahue, PA; Derrick J. Todd, MD, PhD; Andrew Werchniak, MD; Ruth Ann Vleugels, MD, MPH

Importance  Ipilimumab, a human monoclonal antibody targeted against cytotoxic T-lymphocyte antigen 4, has shown promise in the treatment of metastatic melanoma. However, given its mechanism of action, immune-related adverse effects have been reported with this therapy. Despite increasing reports of immune-related adverse effects related to ipilimumab therapy, ...

Comment & Response 
Vanessa L. Pascoe, BA; Alexandra B. Kimball, MD, MPH
To the Editor In their recent article, “Scope of Physician Procedures Independently Billed by Mid-Level Providers in the Office Setting,” Coldiron and Ratnarathorn1 describe the expanding scope of dermatologic mid-level practitioners. Specifically, in 2012 physician assistants (PAs) and nurse practitioners (NPs) performed and billed independently for more than 4 million ...
JAMA Dermatology Clinicopathological Challenge 
Syril Keena T. Que, MD; Brett Sloan, MD; Soheil Sam Dadras, MD
Original Investigation 
Junko Takeshita, MD, PhD; Shuwei Wang, MD; Daniel B. Shin, MS; Nehal N. Mehta, MD, MSCE; Stephen E. Kimmel, MD, MSCE; David J. Margolis, MD, PhD; Andrea B. Troxel, ScD; Joel M. Gelfand, MD, MSCE

Importance  Hypertension is prevalent among patients with psoriasis. The effect of psoriasis and its severity on hypertension control is unknown.

Objective  To determine the association between uncontrolled blood pressure and psoriasis, both overall and according to objectively measured psoriasis severity, among patients with diagnosed hypertension.

Design, ...

Case Report/Case Series 
Marina Vita, PhD; Julie C. Tisserand, MSCI; Isaure Chauvot de Beauchêne, PhD; Nicolas Panel, MSCI; Luba Tchertanov, PhD; Julie Agopian, MSCI; Lenaïg Mescam-Mancini, MD; Bernard Fouet, MD; Béatrice Fournier, MD; Patrice Dubreuil, PhD; François Bertucci, MD, PhD; Paulo De Sepulveda, PhD
Includes: Supplemental Content

Importance  The KIT receptor is mutated in approximately 15% of acral, mucosal, and chronic, sun-damaged melanomas. The status of KIT mutations is of interest because they usually are mutually exclusive with N-RAS and B-RAF mutations and because of the availability of KIT kinase inhibitors in the clinic. ...

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