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 Showing 1-20 of 89 Articles
Original Investigation 
Jonathan I. Silverberg, MD, PhD, MPH; Lauren Becker, MD; Mary Kwasny, ScD; Alan Menter, MD; Kelly M. Cordoro, MD; Amy S. Paller, MS, MD
Includes: Supplemental Content

Importance  Atopic dermatitis (AD) is associated with multiple potential risk factors for obesity and high blood pressure (BP), including chronic inflammation, sleep disturbance, and mental health comorbidity. Previous studies found associations between general obesity and AD. However, it is unknown whether AD is associated with central obesity ...

Case Report/Case Series 
Keshavamurthy Vinay, MD; Amrinder J. Kanwar, MD, FRCP; Ankit Mittal, MD; Sunil Dogra, MD, FRCP; Ranjana W. Minz, MD; Takashi Hashimoto, MD

Importance  Oral lesions of pemphigus vulgaris are usually recalcitrant and respond slowly to treatments. Corticosteroid injection is considered to be the most effective local treatment in oral pemphigus vulgaris. However, intralesional corticosteroids are not effective in all remnant lesions. In 3 such patients with pemphigus vulgaris, we ...

JAMA Dermatology Clinicopathological Challenge 
K. Maharaja, MD; Vishal Gupta, MD; Sujay Khandpur, MD
This nonhealing tongue ulcer was asymptomatic and had a clean base and irregular and elevated heaped-up margins but no underlying induration, friability, or bleeding on manipulation. What is your diagnosis?
Research Letter 
Gery P. Guy Jr, PhD, MPH; Zahava Berkowitz, MSc, MSPH; Sherry Everett Jones, PhD, MPH, JD; Dawn M. Holman, MPH; Erin Garnett, MPH; Meg Watson, MPH
Indoor tanning increases the risk of skin cancer, particularly among frequent users and those initiating use at a young age.1,2 While previous research has demonstrated that indoor tanning is common among youth,3 to our knowledge, this study provides the first national estimates of indoor tanning trends among this population.
Invited Commentary 
Dawn Davis, MD
Pediatric atopic dermatitis (AD) is a cumbersome disease that has medical and psychosocial consequences for the child and family unit. With an ever-increasing prevalence, currently 10.7% in the United States,1 AD is managed by numerous medical professionals, most of whom are not dermatologists. Nonetheless, management of AD by dermatologists is ...
Observation 
Ralph P. Braun, MD; Ashfaq Marghoob, MD
Acquiring digital dermoscopy images has become routine practice in the offices of many dermatologists around the world. While the main purposes of acquiring digital dermoscopy images are documentation and short- and long-term monitoring,1,2 these images can be enhanced to magnify features or sharpen contrast, making it easier to better visualize ...
Case Report/Case Series 
Claudia Günther, MD; Nicole Berndt, MSc; Christine Wolf, MSc; Min Ae Lee-Kirsch, MD
Includes: Supplemental Content

Importance  Familial chilblain lupus is a rare, autosomal dominant form of lupus erythematosus characterized by cold-induced inflammatory lesions at acral locations presenting in early childhood. Familial chilblain lupus is usually caused by a mutation in TREX1 (3′ repair exonuclease 1).

Observations  We report on a family ...

Review 
April W. Armstrong, MD, MPH; Jerry Bagel, MD; Abby S. Van Voorhees, MD; Andrew D. Robertson, PhD; Paul S. Yamauchi, MD

Importance  While monotherapy with biologic agents is effective for many patients with psoriasis, some patients require combination therapy. Evidence-based recommendations on combination therapy provide guidance for treating appropriately selected patients with psoriasis.

Objective  To make evidence-based, best-practice recommendations regarding combining biologics with other systemic treatments, including ...

Review 
Elizabeth Yim, MPH; Robert S. Kirsner, MD, PhD; Robert S. Gailey, PhD, PT; David W. Mandel, PhD, PT; Suephy C. Chen, MD, MS; Marjana Tomic-Canic, PhD

Importance  Patients with venous leg ulcers (VLUs) have calf muscle pump dysfunction, which is associated with reduced ankle range of motion (ROM). Physical therapy or exercise that targets ankle joint mobility may lead to improvement in calf muscle pump function and subsequent healing. However, little is known ...

JAMA Dermatology Clinicopathological Challenge 
Karen Itumeleng Mosojane, MSV; Lara Wine Lee, MD, PhD; Carrie L. Kovarik, MD
Research Letter 
Martina Sanlorenzo, MD; Igor Vujic, MD; Christian Posch, MD; James E. Cleaver, PhD; Pietro Quaglino, MD; Susana Ortiz-Urda, MD, PhD
Recently, a meta-analysis reported an increased incidence of melanoma in pilots and cabin crew, which was possibly due to occupational exposures.1 Cabin crews’ exposure to cosmic radiation was assessed in different studies and always found below the allowed dose limit.2 However, the cumulative exposure of pilots and cabin crew to ...
Invited Commentary 
Joseph McCulloch, PT, PhD, CWS, FAPTA; Edward Mahoney, PT, DPT, CWS; Stanley McCallon, PT, DPT, CWS
The role of the calf muscle pump in addressing complications associated with ambulatory venous hypertension and venous leg ulcers (VLUs) has received a great deal of attention in recent years. Any serious look at the rehabilitation of individuals with calf muscle pump dysfunction should logically include the expertise of a ...
Observation 
Brian J. Simmons, BS; Robert D. Griffith, MD; Leyre A. Falto-Aizpurua, MD; Keyvan Nouri, MD
Envenomation by jellyfish is a common occurrence affecting millions of individuals yearly. Little literature exists on jellyfish stings caused by the “moon jellyfish,” Aurelia aurita. The main objective of the present report is to illustrate that A aurita stings are not as benign as once thought and to propose a ...
Original Investigation 
Jonathan I. Silverberg, MD, PhD, MPH; Amy S. Paller, MD, MS
Includes: Supplemental Content

Importance  Atopic dermatitis (eczema) is a chronic inflammatory disorder that is associated with other chronic diseases (eg, asthma), major quality-of-life impairment, sleep disturbance, and the use of potent topical and sometimes systemic corticosteroids, all of which might affect growth in childhood and adolescence. However, previous smaller-scale studies ...

The Cutting Edge 
Savita Yadav, MD; Sunil Dogra, MD, DNB; Dipankar De, MD; Uma Nahar Saikia, MD
Includes: Supplemental Content
Orofacial granulomatosis (OFG), also termed granulomatous cheilitis, oral granulomatosis, and cheilitis granulomatosa, is an uncommon disorder. The presentation can be very varied; pathogenesis is not very clear; and the treatment result is often disappointing. It is characterized by persistent enlargement of the soft tissues of the lip, oral mucosa, and ...
JAMA Dermatology Clinicopathological Challenge 
Guillermo Solano-López, MD; María José Concha-Garzón, MD; Javier Sánchez-Pérez, MD
Research Letter 
Susan A. Oliveria, ScD, MPH; Nandini Selvam, PhD, MPH; Darius Mehregan, MD; Michael A. Marchetti, MD; Hozefa A. Divan, PhD; Bahar Dasgeb, MD; Allan C. Halpern, MD, MS
The increase in incidence and mortality of melanoma over the past 30 years has heightened public and physician awareness. It is suggested that the combination of increasing detection pressure and poor specificity of current diagnostic strategies is driving biopsy rates to alarming levels in younger individuals despite a low risk ...
Observation 
Daphné Denis, MD; Nathalie Franck, MD; Fanny Fichel, MD; Charlène Levi, MD; Nicolas Dupin, MD
Vemurafenib is a BRAF inhibitor approved by the US Food and Drug Administration as treatment for patients with unresectable or metastatic melanoma harboring the BRAF V600 mutation.1 Recently, vemurafenib-associated renal toxic effects have been reported.2- 4 We describe herein a patient exhibiting Fanconi syndrome as a new renal adverse event ...
Original Investigation 
Girish C. Mohan, MD; Jonathan I. Silverberg, MD, PhD, MPH
Includes: Supplemental Content

Importance  Previous studies found conflicting results as to whether atopic dermatitis (AD) is increased in patients with vitiligo and alopecia areata (AA).

Objective  To compare the prevalence of AD between patients with either vitiligo or AA and those without these disorders by performing a meta-analysis of ...

Case Report/Case Series 
Francesco Lacarrubba, MD; Anna Elisa Verzì, MD; Giuseppe Micali, MD

Importance  Recent studies have reported “comma hairs” as a typical dermoscopic feature of tinea capitis observed at low magnification (×10). The aim of this study was to evaluate the dermoscopic aspects of tinea capitis at high magnification (×150) and its diagnostic role.

Observations  Five children (2 ...

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