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 Showing 1-20 of 65 Articles
Original Investigation  FREE
Andrew Lee, MBBS, MMed; Saxon D. Smith, MBChB, MHL, GAICD, FACD; Esther Hong, MBBS, MPhil, FACD; Sarah Garnett, BSc, MNutr Diet, PhD; Gayle Fischer, MBBS(Hons), MD, FACD

Importance  Increasing evidence suggests that psoriasis poses a cardiometabolic risk in children, as in adults. The best way to screen for this has not yet been established. Waist-to-height ratio (WtHR) can easily identify children with increased central adiposity and is a simpler alternative to body mass index ...

JAMA Dermatology Clinical Evidence Synopsis 
Gill Norman, PhD; Jo C. Dumville, PhD; Emma J. Crosbie, PhD

Clinical Question  Do antiseptics and antibiotics benefit surgical wounds healing by secondary intention (SWHSI)?

Bottom Line  No high-quality randomized clinical trials have addressed this question. Current evidence is limited and insufficient; it is uncertain whether treating SWHSI with antiseptics or antibiotics is beneficial.

JAMA Dermatology Clinicopathological Challenge 
Stacy Reichel, DO; Jeffrey Kushner, DO; Ann Ammond LaFond, MD

A man in his 50s presented with a keratotic plaque with central ulceration that expressed a straw-colored fluid on the left lower leg. What is your diagnosis?

Jennifer N. Saultz, DO; Ben H. Kaffenberger, MD; Montoya Taylor, MD; Nyla A. Heerema, PhD; Rebecca Klisovic, MD

This case report describes a patient with novel chromosome 5 inversion associated with PDGFRB rearrangement in hypereosinophilic syndrome.

Kate E. Oberlin, MD; Erin X. Wei, MD; Jeong Hee Cho-Vega, MD, PhD; Antonella Tosti, MD

This case report describes resolution of nail changes of systemic amyloidosis after bone-marrow transplantation in a patient with multiple myeloma.

Original Investigation 
Ellen N. Pritchett, MD, MPH; Alden Doyle, MD, MPH; Christine M. Shaver, MD; Brett Miller, MD; Mark Abdelmalek, MD; Carrie Ann Cusack, MD; Gregory E. Malat, PharmD; Christina Lee Chung, MD

Importance  Organ transplant recipients have a higher incidence of skin cancer. This risk is magnified over time and with continued exposure to immunosuppression. Skin cancer in nonwhite patients is associated with greater morbidity and mortality owing to diagnosis at a more advanced stage, which suggests that nonwhite ...

JAMA Dermatology Clinicopathological Challenge 
Julia Wu, MD; Rebecca Baxt, MD, MBA; Mark Jacobson, MD

A young woman had a painful erythematous eruption over her thighs that was worse during winter but no other symptoms; she was a nonsmoker, took no medications, and worked at a horse stable and rode for many hours a day. What is your diagnosis?

Research Letter 
Vinayak K. Nahar, MD, MS, PhD; Meagen Rosenthal, PhD; Stephenie C. Lemon, PhD; Dawn M. Holman, MPH; Meg Watson, MPH; Joel J. Hillhouse, PhD; Sherry L. Pagoto, PhD

This survey study evaluates the tanning practices, reasons for tanning, and association with tanning addiction of adults who use tanning beds in private residences.

Belen Rubio-Gonzalez, MD; Jasmine Zain, MD; Lino Garcia, MS; Steven T. Rosen, MD; Christiane Querfeld, MD, PhD

This case report describes a case of cutaneous gamma-delta T-cell lymphoma successfully treated with brentuximab vedotin.

Original Investigation 
Audrey A. Jacobsen, BA; Ana Galvan, BS; Claudina Canaan Lachapelle, MD; Cheryl B. Wohl, MPH; Robert S. Kirsner, MD, PhD; John Strasswimmer, MD, PhD

Importance  As the minority population increases in the United States, the incidence of skin cancer has important public health consequences, including poor skin cancer outcomes, in part because of late-stage diagnosis. Therefore, it is important to identify obstacles in skin cancer prevention in these communities.

Objective  ...

JAMA Dermatology Clinicopathological Challenge 
Emily M. Erstine, MD, MBA; Angela M. B. Collie, MD, PhD; Melissa P. Piliang, MD

A man in his 60s presented with low-grade fevers, unintentional 80-pound weight loss, productive cough, and development of cutaneous ulcers over a 6-month period. What is your diagnosis?

Research Letter 
Mary E. Logue, BA; Tyler Hough, BS; Yuridia Leyva, MS; Jaron Kee, BS; Marianne Berwick, PhD, MPH

This study surveys Southwestern American Indian and non-Hispanic white individuals in New Mexico regarding sun-protective behaviors.

Michael A. Cardis, MD; Helena B. Pasieka, MD, MS

This case report describes the occurrence of adverse effects after application of topical neuromodulators for the treatment of pruritus.

Original Investigation 
Euphemia W. Mu, MD; Jesse M. Lewin, MD; Mary L. Stevenson, MD; Shane A. Meehan, MD; John A. Carucci, MD, PhD; Daniel S. Gareau, PhD, MCR
Includes: Supplemental Content

Importance  Confocal microscopy has the potential to provide rapid bedside pathologic analysis, but clinical adoption has been limited in part by the need for physician retraining to interpret grayscale images. Digitally stained confocal mosaics (DSCMs) mimic the colors of routine histologic specimens and may increase adaptability of ...

JAMA Dermatology Clinicopathological Challenge 
Jihane Abou Rahal, MD; Olivier Cogrel, MD; Bernard Cribier, MD, PhD

A woman in her 20s presented with multiple facial papules since childhood that progressively increased in number. What is your diagnosis?

Research Letter 
Matan Rothschild, MD; Greg Duhon, MD; Rashid Riaz, MD; Vybhav Jetty, MD; Naila Goldenberg, MD; Charles J. Glueck, MD; Ping Wang, PhD

This case series describes palmar crease xanthomas and other dermatologic manifestations of familial dysbetalipoproteinemia and mutant apoE2/2 genotype.

Warren R. Heymann, MD

This case report describes a case of a dermatologic cyst interpreted as an airport security threat.

Viewpoint  FREE
Gery P. Guy Jr, PhD, MPH; Dawn M. Holman, MPH; Meg Watson, MPH

This Viewpoint discusses the important role of schools in the prevention of skin cancer.

To make a definitive diagnosis of skin cancer, dermatologists have been required to obtain skin biopsy specimens of suspicious lesions and to examine tissue pathologic abnormalities ex vivo under light microscopy. In the past decades, high diagnostic sensitivity, which is associated with a low biopsy threshold,1 has ...

Original Investigation 
Stefania Borsari, MD; Riccardo Pampena, MD; Aimilios Lallas, MD; Athanassios Kyrgidis, MD; Elvira Moscarella, MD; Elisa Benati, MD; Margherita Raucci, ARNP; Giovanni Pellacani, MD; Iris Zalaudek, MD; Giuseppe Argenziano, MD; Caterina Longo, MD, PhD
Includes: Supplemental Content

Importance  Reflectance confocal microscopy (RCM) improves diagnostic accuracy in skin cancer detection when combined with dermoscopy; however, little evidence has been gathered regarding its real impact on routine clinical workflow, and, to our knowledge, no studies have defined the terms for its optimal application.

Objective  To ...

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