TY - JOUR T1 - A randomized double-blind study of the effect of botox and dysport/reloxin on forehead wrinkles and electromyographic activity AU - Karsai S, Adrian R, Hammes S, Thimm J, Raulin C Y1 - 2007/11/01 N1 - 10.1001/archderm.143.11.1447-b JO - Archives of Dermatology SP - 1447 EP - 1462 VL - 143 IS - 11 N2 - The difference between the potency units of the 2 main botulinum toxin A products, Botox (Allergan, Irvine, California) and Dysport/Reloxin (Ipsen Ltd, Slough, England), is still a subject of discussion even after 15 years of clinical use. The manufacturer of Botox recommends higher ratios than does the manufacturer of Dysport/Reloxin. Herein, we report the findings of a randomized, double-blind, split-face study of forehead wrinkles and electromyographic (EMG) activity following application of the 2 products at a 3:1 dose ratio, independent of the support of either manufacturer. SN - 0003-987X M3 - doi: 10.1001/archderm.143.11.1447-b UR - http://dx.doi.org/10.1001/archderm.143.11.1447-b ER -