TY - JOUR T1 - Squamous cell carcinoma of the lower lip involving a large cutaneous surface: Photodynamic therapy as an alternative therapy AU - Gross DJ, Waner M, Schosser RH, Dinehart SM Y1 - 1990/09/01 N1 - 10.1001/archderm.1990.01670330028002 JO - Archives of Dermatology SP - 1148 EP - 1150 VL - 126 IS - 9 N2 - A 72-year-old white man complained of redness, soreness, and irritation of his lower lip for more than 10 years. Physical examination revealed a diffuse erythematous crusted patch involving the lower lip, with a 1.2-cm centrally located palpable area (Fig 1). Cervical adenopathy was not noted. A biopsy performed in 1981 showed actinic keratosis, and the area was treated with liquid nitrogen and fluorouracil. In 1985, two lip biopsy specimens showed squamous cell carcinoma in situ, and actinic keratosis with severe dysplasia, for which he was treated with liquid nitrogen. Several lip biopsy specimens obtained in 1988 demonstrated ulcerated squamous cell carcinoma, Broder's grade 1. The tumor was 0.9 cm at its greatest depth.At about the same time, a 2-cm noncalcified nodule in the right middle lobe was seen on a chest roentgenogram ordered as preoperative screening for cataract surgery, and it was feared that squamous cell carcinoma had metastasized SN - 0003-987X M3 - doi: 10.1001/archderm.1990.01670330028002 UR - http://dx.doi.org/10.1001/archderm.1990.01670330028002 ER -