TY - JOUR T1 - ELastosis perforans serpiginosa AU - Carey TD Y1 - 1977/10/01 N1 - 10.1001/archderm.1977.01640100122027 JO - Archives of Dermatology SP - 1444 EP - 1445 VL - 113 IS - 10 N2 - Elastosis perforans serpiginosa (EPS), a rare disease, has been associated with mongolism and several connective tissue disorders, including osteogenesis imperfecta, pseudoxanthoma elasticum, Marfan syndrome, and Ehlers-Danlos syndrome. The first description of EPS was made by Lutz in 1953.1 Two years later, Miescher2 presented a complete histopathologic study. The first cases of EPS in the United States were described by Hitch and Lund in 1959.3To my knowledge, this is the third patient reported to have EPS coincident with osteogenesis imperfecta, which is a generalized disorder of connective tissue involving the fascia, ligaments, skin, sclera, tendons, inner ears, and bones, that typically results in the patient's having blue sclera and brittle bones.4REPORT OF A CASEĀ  A 17-year-old boy had had blue sclerae since infancy. As a child, he had had several fractures, and x-ray films taken on each occasion were consistent with the diagnosis of osteogenesis SN - 0003-987X M3 - doi: 10.1001/archderm.1977.01640100122027 UR - http://dx.doi.org/10.1001/archderm.1977.01640100122027 ER -