TY - JOUR T1 - CHicago dermatological society AU - Neuhauser I, Bluefarb SM Y1 - 1956/03/01 N1 - 10.1001/archderm.1956.01550030085020 JO - A.M.A. Archives of Dermatology SP - 283 EP - 286 VL - 73 IS - 3 N2 - Pityriasis Lichenoides et Varioliformis Acuta. Presented by Dr. Louis Rubin, Rockford, Ill.A 23-year-old white man states he had no cutaneous eruption prior to about March 1, 1955. At that time he developed a dry scaly lesion on his right thigh, and a few days later a generalized, erythematous, papular eruption. There were no premonitory symptoms.At present on his neck, trunk, arms, upper legs, and areas of feet he has erythematous papules up to about 8 mm. in diameter. Many lesions have hemorrhagic centers and hemorrhagic crusts. Some lesions have become ulcerated, and a few have a suggestion of a vesicular center. Pruritus is marked.Biopsy section shows the epidermis to be necrotic in one area. Bordering this there are large swollen epithelial nuclei and pale-staining binucleate cells. The cytoplasm of some epithelial cells is condensed and assumes the appearance of individual cell keratinization. Many of the SN - 0096-5359 M3 - doi: 10.1001/archderm.1956.01550030085020 UR - http://dx.doi.org/10.1001/archderm.1956.01550030085020 ER -