TY - JOUR T1 - ECzema solare and porphyria AU - TEMPLETON HJ, LUNSFORD CJ Y1 - 1932/04/01 N1 - 10.1001/archderm.1932.01450020713007 JO - Archives of Dermatology and Syphilology SP - 691 EP - 703 VL - 25 IS - 4 N2 - Bazin1 first suggested, in 1855, the possibility that sunlight acting on a sensitive skin could produce various types and degrees of harmful reactions. In 1898, McCall Anderson2 introduced the thought that some photosensitizing substance might play a rôle in such cases, but it remained for Ehrmann3 to demonstrate the presence of such an agent, hematoporphyrin, in hydroa vacciniforme. Since then many cases of hydroa vacciniforme associated with hematoporphyria have been reported in the literature. Various authors have assigned to this photosensitizing substance the rôle of etiologic agent in such cases. It is important, however, to note that the substance has been demonstrated in only approximately 25 per cent of the cases.4 Moreover, many cases of hydroa vacciniforme have occurred in which attempts to demonstrate hematoporphyrin have failed.5 Klauder6 reported a case of hydroa in which hematoporphyrin was present in some samples of urine SN - 0096-6029 M3 - doi: 10.1001/archderm.1932.01450020713007 UR - http://dx.doi.org/10.1001/archderm.1932.01450020713007 ER -