TY  - JOUR
T1  - A retrospective analysis of patients with bullous pemphigoid treated with methotrexate
AU  - Kjellman P, Eriksson H, Berg P
Y1  - 2008/05/01
N1  - 10.1001/archderm.144.5.612
JO  - Archives of Dermatology
SP  - 612
EP  - 616
VL  - 144
IS  - 5
N2  - Objectives 
    To evaluate treatment with methotrexate in patients with bullous pemphigoid and to elucidate the reduced adverse effects compared with standard treatment with prednisone.Design 
    Retrospective study (January 1, 1999-December 31, 2003).Setting 
    The Department of Dermatology and Venerology, Karolinska University Hospital.Patients 
    A total of 138 consecutive patients with bullous pemphigoid were included and were grouped according to the treatment they received: methotrexate, prednisone, a combination of both, or topical glucocorticoids (for mild disease).Result 
    Methotrexate was the most effective treatment, with only a few adverse effects and a tendency toward better survival rates in patients with moderate to severe disease.Conclusion 
    Methotrexate is an effective and safe drug and provides an excellent treatment option in patients with bullous pemphigoid.
SN  - 0003-987X
M3  - doi: 10.1001/archderm.144.5.612
UR  - http://dx.doi.org/10.1001/archderm.144.5.612
ER  -