RT Journal
A1 LINDSAY DG, BECKER S, WILSON J
T1 TReatment of cutaneous trichophyton rubrum infection with human immune globulin
JF Archives of Dermatology
JO Archives of Dermatology
YR 1960
FD April 1
VO 81
IS 4
SP 586
OP 590
DO 10.1001/archderm.1960.03730040090016
UL http://dx.doi.org/10.1001/archderm.1960.03730040090016
AB Our interest in the treatment of cutaneous Trichophyton rubrum infection by injection of λ-globulin was aroused when Shector, et al.1 reported a remarkable therapeutic and laboratory result in a patient so treated. A man, aged 50, had had erythematous, scaling plaques over the neck and upper back and on the right lower abdomen for seven years, which had partially faded during the winter months, but became more pronounced during the summer. Itching was severe enough to awaken him at night. Various locally applied antifungal remedies had failed to cure the disorder. Culture revealed T. rubrum from both plaques. He was given 2.0 ml. of human λ-globulin intramuscularly three times weekly for a total of 12 treatments. Within 48 hours after the first injection, pruritus was relieved and the involved areas became less erythematous. After the second injection, both plaques appeared normal. Three months later, the skin still appeared normal,