RT Journal
A1 PIPER EL
T1 ACrodermatitis enteropathica in an adult
JF A.M.A. Archives of Dermatology
JO A.M.A. Archives of Dermatology
YR 1957
FD August 1
VO 76
IS 2
SP 221
OP 224
DO 10.1001/archderm.1957.01550200065014
UL http://dx.doi.org/10.1001/archderm.1957.01550200065014
AB IntroductionAcrodermatitis enteropathica has been recognized as a rare clinical entity distinct from epidermolysis bullosa dystrophica since 1942, when Danbolt and Closs1 classically described the disease. Prior to that time Wende2 and Brandt3 had reported bizarre bullous dermatoses, which in retrospect were acrodermatitis enteropathica. Diiodohydroxyquin (Diadoquin) was found by Schlomovitz4 to be an effective therapeutic agent. Subsequent reports by Dillaha and Lorincz,5 Bloom and Sobel,6 and HodgsonJones7 confirm its successful action.The following case report of acrodermatitis enteropathica is unique. The patient is a 46-year-old woman who has had a mild intermittent form of the disease most of her life. The histopathology of the disorder is reported in detail. Diiodohydroxyquin has resulted in a remission of the disease.Report of a CaseA married woman, age 46, was first seen in August, 1956, with a dermatitis involving the distal