RT Journal
A1 del Giudice P, Hubiche T, Etienne J
T1 Long-term use of tetracycline and staphylococcus aureus tetracycline resistance: Not only a problem of acne
JF Archives of Dermatology
JO Archives of Dermatology
YR 2012
FD March 1
VO 148
IS 3
SP 402
OP 402
DO 10.1001/archdermatol.2011.3099
UL http://dx.doi.org/10.1001/archdermatol.2011.3099
AB 
We read with great interest the study by Fanelli et al1 showing that the prolonged use of tetracycline antibiotic, commonly used to treat acne, lowered the incidence of colonization by Staphylococcus aureus and did not increase resistance to the tetracycline antibiotics, but these results should be taken cautiously. Apart from acne, there is another circumstance in which tetracycline antibiotics are prescribed over a long period, namely for the prevention of malaria. In this context, the use of doxycycline, 100 mg/d, is currently indicated to prevent malaria attack for travelers in areas where malaria is endemic. In particular, the French military routinely use doxycycline as malaria prophylaxis.