A 32-year-old female smoker presented with a 3-day history of painful ulceration and cracking of her lips (Figure 1). Her medical history included a 12-year history of systemic lupus erythematosus (SLE), well controlled by treatment with 200 mg/d of hydroxychloroquine and 5 mg/d of prednisone. She practiced conscientious sun protection with a hat and broad-spectrum sunscreen. She denied the use of new topical products.
Figure 1.
Physical examination revealed numerous confluent erosions of the upper and lower lips, with overlying serosanguineous crust, clustered near the vermillion border. In the oral cavity, there were erosions of the labial and buccal mucosa, with sparing of the gingival mucosa. Two 2-mm punch biopsy specimens were obtained: one from the upper lip for hematoxylin-eosin staining, the other from the lower lip for direct immunofluorescence microscopy (Figure 2 and Figure 3).
Figure 2.
Figure 3.
Article
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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