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Correspondence |

Alcohol Intake and Risk of Psoriasis: Smoking as a Confounding Factor

Shawn G. Kwatra, BS
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Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

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Arch Dermatol. 2011;147(3):358-358. doi:10.1001/archdermatol.2011.15
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I read with great interest the study by Qureshi et al1 published in the Archives and also highlighted in the New York Times.2 The study concluded that women who drink more than 5 nonlight beers per week have an increased risk of developing psoriasis. However, this finding may be flawed.

The authors did not provide data on the incidence of smoking in those women who drank more than 5 nonlight beers per week. The percentage of smokers in this group is likely to be very high, given that the percentage of smokers among those who drink more than 2.3 alcoholic beverages of all kinds was 37%, compared with a 22% smoking rate among those who drink between 1.2 and 2.3 alcoholic beverages a week.1 Furthermore, it can be expected that beer drinkers smoke more than wine drinkers because wine drinkers adopt healthier lifestyles, including exercising more and smoking less,3 a finding that could further confound the association between beer drinking and psoriasis.

More importantly, the authors did not segregate patients on the basis of current smoking intensity (number of cigarettes per day) and duration (number of pack-years). This is important, given that there is a known association between smoking and psoriasis.4 Proper analysis of the extent of smoking habits among women in the study who drank more than 5 nonlight beers per week may reveal that smoking status was a confounding variable that distorted the study's results.

AUTHOR INFORMATION

Correspondence: Mr Kwatra, Wake Forest University School of Medicine, 100 Medical Center Blvd, Winston-Salem, NC 27157-1071 (skwatra@wfubmc.edu).

Financial Disclosure: None.

REFERENCES

Qureshi  AA, Dominguez  PL, Choi  HK, Han  J, Curhan  G. Alcohol intake and risk of incident psoriasis in US women: a prospective study. Arch Dermatol 2010;146 (12) 1364- 1369
PubMed
Rabin  RC. Risks: full-calorie beer has a link to psoriasis. http://www.nytimes.com/2010/08/24/health/24risk.html?_r=2&scp=1&sq=psoriasis&st=cse. Accessed August 25, 2010
Paschall  M, Lipton  RI. Wine preference and related health determinants in a U.S. national sample of young adults. Drug Alcohol Depend 2005;78 (3) 339- 344
PubMed
Setty  AR, Curhan  G, Choi  HK. Smoking and the risk of psoriasis in women: Nurses' Health Study II. Am J Med 2007;120 (11) 953- 959
PubMed

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Qureshi  AA, Dominguez  PL, Choi  HK, Han  J, Curhan  G. Alcohol intake and risk of incident psoriasis in US women: a prospective study. Arch Dermatol 2010;146 (12) 1364- 1369
PubMed
Rabin  RC. Risks: full-calorie beer has a link to psoriasis. http://www.nytimes.com/2010/08/24/health/24risk.html?_r=2&scp=1&sq=psoriasis&st=cse. Accessed August 25, 2010
Paschall  M, Lipton  RI. Wine preference and related health determinants in a U.S. national sample of young adults. Drug Alcohol Depend 2005;78 (3) 339- 344
PubMed
Setty  AR, Curhan  G, Choi  HK. Smoking and the risk of psoriasis in women: Nurses' Health Study II. Am J Med 2007;120 (11) 953- 959
PubMed

Correspondence

March 1, 2011
Abrar A. Qureshi, MD, MPH; Tricia Li, MD, MSc; Jiali Han, PhD
Arch Dermatol. 2011;147(3):358-359. doi:10.1001/archdermatol.2011.16.
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