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Generalized Blue-Gray Pigmentation—Quiz Case

Suraj G. Reddy, MD; John M. Martin, IV, BS; Eric W. Kraus, MD; Jeffrey J. Meffert, MD
[+] Author Affiliations

Mary S. Stone, MD

Soon Bahrami, MD
Carrie Ann R. Cusack, MD
Senait W. Dyson, MD
Molly A. Hinshaw, MD
Vincent Liu, MD

Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

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Arch Dermatol. 2009;145(9):1053-1058. doi:10.1001/archdermatol.2009.182-a
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REPORT OF A CASE

A 61-year-old man presented with a 5-year history of progressive blue-gray pigmentation involving his face, chest, and extremities in a sun-exposed distribution. He reported a history of respiratory infections that had been treated with various antibiotics. After losing his medical insurance, he resorted to alternative remedies to treat his respiratory ailments. He was not taking any prescription medications, and his medical history was remarkable for diverticulitis and cardiac bypass surgery.

Physical examination revealed diffuse blue-gray pigmentation involving the face, sclera, conjunctiva, gingiva, soft palate, upper chest area, back, arms, and nails (Figure 1). A preauricular punch biopsy specimen was obtained for analysis (Figure 2 and Figure 3). The results of laboratory investigations, including a complete blood cell count, chemistry panel, liver function tests, and thyroid levels, were all within normal limits.

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To understand the clinical management of acute heart failure syndromes.
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