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Brown Macules Symmetrically Distributed on the Neck, Axillae, and Thighs—Quiz Case

Lucy Li, MD; Walter K. Nahm, MD, PhD; Paula Moskowitz, MD, PhD; Evangelos Badiavas, MD, PhD; Jane Danahy, MD
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Michael E. Ming, MD
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Copyright 2003 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

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Arch Dermatol. 2003;139(5):657-662. doi:10.1001/archderm.139.5.657-a
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REPORT OF A CASE

A 50-year-old white woman presented with tan-brown spots on her neck, chest, axillae, and groin area that had gradually developed over a period of more than 10 months. The lesions were mostly asymptomatic but were occasionally itchy. The patient was otherwise healthy. Her mother had similar lesions, mostly restricted to the arms, and her grandfather had similar lesions over almost all of his body.

Physical examination revealed 2- to 5-mm brown macules, some of which were slightly hyperkeratotic, distributed symmetrically over the lateral aspect of the neck, axillae, chest, and inner area of the thighs (Figure 1 and Figure 2).

A 4-mm punch biopsy specimen from a lesion on the inner thigh was stained with hematoxylineosin (Figure 3 and Figure 4).

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

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To understand the clinical management of acute heart failure syndromes.
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