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Blei et al1 reported the rare familial occurrence of hemangiomas and/or vascular malformations in 6 kindreds. The vascular lesions appeared to be transmitted in an autosomal dominant fashion with moderate to high penetrance.
In 283 patients with port-wine stains attending a laser clinic, we studied the family history of birthmarks.2 We were surprised to find that 72 patients (25.4%) had a family history of birthmarks, and 42 (15%) had a family history of vascular birthmarks; 20 of those were strawberry hemangiomas and 22 (7%) were port-wine stains. The figures for port-wine stains are higher than expected from the prevalence in the population, and our patients, like those in the study by Blei et al,1 had vascular malformations and hemangiomas present in different members of the same family.
We congratulate Blei et al on their important observations, and we entirely agree with their advice that physicians caring for children with hemangiomas and vascular malformations should include in their medical histories inquiries about vascular lesions in other family members.
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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