0
August 1997, Vol 133, No. 8 >
Article | August 1997

Mycobacterium marinum Skin Infection Successfully Treated With Levofloxacin

Shigeruko lijima, MD; Junko Saito, MD; Fujio Otsuka, MD
[+] Author Affiliations

Department of Dermatology, University of Tsukuba, Tsukuba, Japan


Arch Dermatol. 1997;133(8):947-949. doi:10.1001/archderm.1997.03890440013001
Text Size: A A A
Published online
Article
References
Comments

REPORT OF A CASE  A 30-year-old Japanese man first noticed a small, slightly pruritic nodule on the dorsum of his left hand in December 1993. Before the patient presented to us in May 1994 he was treated by his personal physician, who prescribed several antibiotics for 2 months without apparent response. The nodule slowly grew and became tender. Another small nodule then appeared on his left forearm. The patient had kept tropical fish for 5 years and he reported injuring his left hand when cleaning the fish tank.A physical examination revealed 2 dark, erythematous, and slightly elevated nodules that measured 37×17 mm on the dorsum of his left hand and 47×25 mm on his forearm (Figure 1). Both nodules were exudative and purulent. The superficial regional lymph nodes were not swollen.Results of the laboratory examination, which included a complete blood cell count with differentiation, blood chemistry profile, and

REFERENCES

1 +
Edelstein H.  Mycobacterium marinum skin infections: report of 31 cases and review of the literature . Arch Intern Med. 1994;;154:1359-1364.
2 +
Kullavanijaya P, Sirimachan S, Bhuddhavudhikrai P.  Mycobacterium marinum cutaneous infections acquired from occupations and hobbies . Int J Dermatol. 1993;;32:504-507.
3 +
Donta ST, Smith PW, Levitz RE, Quintiliani R.  Therapy of Mycobacterium marinum infections: use of tetracyclines vs rifampin . Arch Intern Med. 1986;;146: 902-904.
4 +
Sanders WJ, Wolinsky E.  In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents . Antimicrob Agents Chemother. 1980;;18:529-531.
5 +
Arai H, Nakajima H, Kaminaga Y.  In vitro susceptibility of Mycobacterium marinum to dihydromycoplanecin A and ten other antimicrobial agents . J Dermatol. 1990;;17:370-374.
6 +
Brown BA, Wallace RJ Jr, Onyi GO.  Activities of clarithromycin against eight slowly growing species of nontuberculous mycobacteria, determined by using a broth microdilution MIC system . Antimicrob Agents Chemother. 1992;;36:1987-1990.
7 +
Kuhn SM, Rosen W, Wong A, Jadavji T.  Treatment of Mycobacterium marinum facial abscess using clarithromycin . Pediatr Infect Dis J. 1995;;14:631-632.
8 +
Leysen DC, Haemers A, Pattyn SR.  Mycobacteria and the new quinolones . Antimicrob Agents Chemother . 1989;;33:1-5.
9 +
Garcia-Rodriguez JA, Gomez Garcia AC.  In-vitro activities of quinolones against mycobacteria . J Antimicrob Chemother. 1993;;32:797-808.
10 +
Tomioka H, Sato K, Saito H.  Comparative in vitro and in vivo activity of fleroxacin and ofloxacin against various mycobacteria . Tubercle. 1991;;72:176-180.
11 +
Saito H, Tomioka H, Sato K, Dekio S.  In vitro and in vivo antimycobacterial activities of a new quinolone, DU-6859a . Antimicrob Agents Chemother. 1994;;38: 2877-2882.
12 +
Ishida M, Takei A, Itoh M, Tsuyuki S, Yamaguchi K.  A case of atypical Mycobacterium infection [in Japanese] . Jpn J Dermatol. 1993;;103:860. Abstract.
13 +
Arai H, lemoto G, Nakajima H, Kaminaga Y.  A case of Mycobacterium marinum skin infection [in Japanese] . Hifubyoh-shinryoh. 1995;;17:379-382.
14 +
Une T, Fujimoto T, Sato K, Osada Y.  In vitro activity of DR-3355, an optically active ofloxacin . Antimicrob Agents Chemother. 1988;;32:1336-1340.
15 +
Fujimoto T, Mitsuhashi S.  In vitro antibacterial activity of DR-3355, the S-(-)— isomer of ofloxacin . Chemotherapy . 1990;;36:268-276.
16 +
Tanaka M, Otsuki M, Une T, Mshino T.  In vitro and in vivo activity of DR-3355, an optically active isomer of ofloxacin . J Antimicrob Chemother. 1990;;26:659-666.
17 +
Takahashi H, Mogi S, Kobayashi M, et al.  Assay of skin level and clinical investigation of levofloxacin in the treatment of skin infections [in Japanese] . Chemotherapy . 1992;;40( (S-3) ):286-305.
18 +
Nakashima M, Uematsu T, Kanamaru M, Okazaki O, Hakusui H.  Phase 1 study of levofloxacin, S—(-)-ofloxacin . Jpn J Clin Pharmacol Ther. 1992;;23:515-520.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Edelstein H.  Mycobacterium marinum skin infections: report of 31 cases and review of the literature . Arch Intern Med. 1994;;154:1359-1364.
2 +
Kullavanijaya P, Sirimachan S, Bhuddhavudhikrai P.  Mycobacterium marinum cutaneous infections acquired from occupations and hobbies . Int J Dermatol. 1993;;32:504-507.
3 +
Donta ST, Smith PW, Levitz RE, Quintiliani R.  Therapy of Mycobacterium marinum infections: use of tetracyclines vs rifampin . Arch Intern Med. 1986;;146: 902-904.
4 +
Sanders WJ, Wolinsky E.  In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents . Antimicrob Agents Chemother. 1980;;18:529-531.
5 +
Arai H, Nakajima H, Kaminaga Y.  In vitro susceptibility of Mycobacterium marinum to dihydromycoplanecin A and ten other antimicrobial agents . J Dermatol. 1990;;17:370-374.
6 +
Brown BA, Wallace RJ Jr, Onyi GO.  Activities of clarithromycin against eight slowly growing species of nontuberculous mycobacteria, determined by using a broth microdilution MIC system . Antimicrob Agents Chemother. 1992;;36:1987-1990.
7 +
Kuhn SM, Rosen W, Wong A, Jadavji T.  Treatment of Mycobacterium marinum facial abscess using clarithromycin . Pediatr Infect Dis J. 1995;;14:631-632.
8 +
Leysen DC, Haemers A, Pattyn SR.  Mycobacteria and the new quinolones . Antimicrob Agents Chemother . 1989;;33:1-5.
9 +
Garcia-Rodriguez JA, Gomez Garcia AC.  In-vitro activities of quinolones against mycobacteria . J Antimicrob Chemother. 1993;;32:797-808.
10 +
Tomioka H, Sato K, Saito H.  Comparative in vitro and in vivo activity of fleroxacin and ofloxacin against various mycobacteria . Tubercle. 1991;;72:176-180.
11 +
Saito H, Tomioka H, Sato K, Dekio S.  In vitro and in vivo antimycobacterial activities of a new quinolone, DU-6859a . Antimicrob Agents Chemother. 1994;;38: 2877-2882.
12 +
Ishida M, Takei A, Itoh M, Tsuyuki S, Yamaguchi K.  A case of atypical Mycobacterium infection [in Japanese] . Jpn J Dermatol. 1993;;103:860. Abstract.
13 +
Arai H, lemoto G, Nakajima H, Kaminaga Y.  A case of Mycobacterium marinum skin infection [in Japanese] . Hifubyoh-shinryoh. 1995;;17:379-382.
14 +
Une T, Fujimoto T, Sato K, Osada Y.  In vitro activity of DR-3355, an optically active ofloxacin . Antimicrob Agents Chemother. 1988;;32:1336-1340.
15 +
Fujimoto T, Mitsuhashi S.  In vitro antibacterial activity of DR-3355, the S-(-)— isomer of ofloxacin . Chemotherapy . 1990;;36:268-276.
16 +
Tanaka M, Otsuki M, Une T, Mshino T.  In vitro and in vivo activity of DR-3355, an optically active isomer of ofloxacin . J Antimicrob Chemother. 1990;;26:659-666.
17 +
Takahashi H, Mogi S, Kobayashi M, et al.  Assay of skin level and clinical investigation of levofloxacin in the treatment of skin infections [in Japanese] . Chemotherapy . 1992;;40( (S-3) ):286-305.
18 +
Nakashima M, Uematsu T, Kanamaru M, Okazaki O, Hakusui H.  Phase 1 study of levofloxacin, S—(-)-ofloxacin . Jpn J Clin Pharmacol Ther. 1992;;23:515-520.

Correspondence

Submit a Letter
CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2012 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems