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Article |

Giant Inflammatory Targetoid Plaques

Lawrence S. Chan, MD
[+] Author Affiliations

University of Michigan School of Medicine, Ann Arbor


Arch Dermatol. 1992;128(7):982-982. doi:10.1001/archderm.1992.01680170115021
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REPORT OF A CASE  A 62-year-old white man presented with an 8-month history of an annular erythematous lesion located on the patient's axilla, chest, and abdomen. Although the annular lesions had slightly enlarged over the 8-month period, they were generally asymptomatic, although with slight tenderness on rubbing. Significant history consisted of rheumatoid arthritis, peripheral neuropathy, and non-insulin-dependent diabetes mellitus; the patient received choline magnesium trisalicylate (Trilisate) and glipizide (Glucotrol) regularly. He denied any history of tick bite, fever, fatigue, pruritus, difficulty in breathing, cough, vision change, or Raynaud's phenomenon.Physical examination revealed several giant annular erythematous lesions on the patient's right axilla, right side of the chest, and abdomen (Fig 1). The individual lesions were annular erythematous nodular plaques with minimal or no scaling. An outer rim of erythema was present in some of the lesions, mimicking targetoid figures (Fig 2). Atrophy, sclerosis, or telangiectasias were not seen. Mucous membrane

REFERENCES

Arnold HL, Odom RB, James WD. Andrew's Diseases of the Skin . Philadelphia, Pa: WB Saunders Co; 1990;:137-310.
Lever WF, Schaumburg-Lever G. Histopathology of the Skin . Philadelphia, Pa: JB Lippincott; 1983;:137-449.
Hood AF, Kwan TH, Burnes DC, Mihm MC. Primer of Dermatopathology . Boston, Mass: Little Brown & Co; 1984;:208-248.
Dabski K, Winkelmann RK.  Generalized granuloma annulare: clinical and laboratory findings in 100 patients . J Am Acad Dermatol. 1989;;20:39-47.
Dahl MV, Goltz RW.  Granuloma annulare . In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF, eds. Dermatology in General Medicine . New York, NY: McGraw-Hill International Book Co; 1987;:1018-1022.
Ma A, Medenica M.  Response of generalized granuloma annulare to high-dose of niacinamide . Arch Dermatol. 1983;;119:836-839.
Steiner A, Pehamberger H, Wolff K.  Sulfone treatment of granuloma annulare . J Am Acad Dermatol. 1985;;13:1004-1008.
Kerker BJ, Huang CP, Morison WL.  Photochemotherapy of generalized granuloma annulare . Arch Dermatol. 1990;;126:359-361.

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Arnold HL, Odom RB, James WD. Andrew's Diseases of the Skin . Philadelphia, Pa: WB Saunders Co; 1990;:137-310.
Lever WF, Schaumburg-Lever G. Histopathology of the Skin . Philadelphia, Pa: JB Lippincott; 1983;:137-449.
Hood AF, Kwan TH, Burnes DC, Mihm MC. Primer of Dermatopathology . Boston, Mass: Little Brown & Co; 1984;:208-248.
Dabski K, Winkelmann RK.  Generalized granuloma annulare: clinical and laboratory findings in 100 patients . J Am Acad Dermatol. 1989;;20:39-47.
Dahl MV, Goltz RW.  Granuloma annulare . In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF, eds. Dermatology in General Medicine . New York, NY: McGraw-Hill International Book Co; 1987;:1018-1022.
Ma A, Medenica M.  Response of generalized granuloma annulare to high-dose of niacinamide . Arch Dermatol. 1983;;119:836-839.
Steiner A, Pehamberger H, Wolff K.  Sulfone treatment of granuloma annulare . J Am Acad Dermatol. 1985;;13:1004-1008.
Kerker BJ, Huang CP, Morison WL.  Photochemotherapy of generalized granuloma annulare . Arch Dermatol. 1990;;126:359-361.

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