Department of Dermatology Utrecht University Hospital Heidelberglaan 100 3584 CX Utrecht, the Netherlands
Department of Dermatology Groningen University Hospital Oostersingel 59 9713 EZ Groningen, the Netherlands
To the Editer. —We read the article by Cobb and coworkers1 in the March 1992 issue of the Archives with interest. This article concerned a patient with Waldenström macroglobulinemia, a pruritic papular eruption, and IgM-K deposits in the epidermal basement membrane zone (BMZ). In 1988, we published an article concerning 25 patients with linear IgM deposits in the epidermal BMZ.2 These deposits were found in- diseased and in clinically healthy skin and tended to persist throughout the years. In 2771 biopsy specimens examined by means of routine immunofluorescence, the frequency of this feature was 0.9% (in comparison, the frequency of bullous pemphigoid was 1.2%; linear IgA dermatosis, 0.01%). We could find no common denominator when reviewing the patients' serologic data and clinical picture. The range of clinical symptoms was as follows: pruritus/urticaria, nine cases; purpura, five cases; vesicles/bullae, four cases; nonspecific rash, three cases; and ulcers, two cases.
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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