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Human Orf

Richard Groves, MRCP; D. M. MacDonald, MA, MB, FRCP; E. Wilson Jones, FRCP, FRCPath
[+] Author Affiliations

Department of Dermatology Guy's Hospital London, England SE1 9RT

Department of Histopathology St John's Dermatology Centre St Thomas Hospital London, England


Arch Dermatol. 1990;126(12):1649-1649. doi:10.1001/archderm.1990.01670360117024
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To the Editor.—  We read with great interest the recent report by Gill et al1 concerning four cases of orf. We would agree with many of their comments and, in particular, it is our impression also that orf is considered too rarely in the differential diagnosis of inflammatory nodules. An awareness of the disease is important for urban as well as rural physicians, as a series of cases has been reported in meat workers in the heart of London, England.2 We do, however, wish to make two further points:The authors give the impression that electron microscopy of fluid from the lesion is the best means of establishing a diagnosis. This is probably not the case, as previous studies have shown that the crust from a lesion contains large amounts of orf virus and is the best tissue to examine electron microscopically.3 These authors report that vesicle

REFERENCES

Gill MJ, Arlette J, Buchan KA, Barber K.  Human orf: a diagnostic consideration? Arch Dermatol. 1990;;126:356-358.
Hodgson Jones IS.  Orf in London . BMJ. 1951;;1:795.
Nagington J.  Electron microscopy in the differential diagnosis of pox virus infections . BMJ. 1964;;2:1499-1500.
Groves RW, Wilson Jones E, MacDonald DM.  Human orf: morphologic characteristics and immunohistochemical diagnosis . J Cutan Pathol. 1989;; 16:305.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Gill MJ, Arlette J, Buchan KA, Barber K.  Human orf: a diagnostic consideration? Arch Dermatol. 1990;;126:356-358.
Hodgson Jones IS.  Orf in London . BMJ. 1951;;1:795.
Nagington J.  Electron microscopy in the differential diagnosis of pox virus infections . BMJ. 1964;;2:1499-1500.
Groves RW, Wilson Jones E, MacDonald DM.  Human orf: morphologic characteristics and immunohistochemical diagnosis . J Cutan Pathol. 1989;; 16:305.

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