Department of Dermatology Royal Free Hospital London, England NW3 2QG
To the Editor.— We were interested to read the article by Wheeland et al1 in the July 1985 issue of the Archives, which described Darier's disease complicated by Trichophyton tonsurans infection. We, too, have encountered chronic dermatophyte infection complicating Darier's disease in two of 17 family members with Darier's disease.2 They were a brother and sister with the typical features of Darier's disease and an associated dyskeratosis of the palms and soles in the form of keratoderma. Both developed a chronic Trichophyton rubrum infection of the palms, soles, and nails. The fungus infection remained refractory to prolonged courses of oral griseofulvin.Patients with Darier's disease are known to be susceptible to viral and bacterial infections of the skin, and this has been attributed to immunodeficiency.3 We share the belief of Wheeland and colleagues that the fungal infection encountered in Darier's disease is probably related to the dyskera
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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