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Familial Urticaria Pigmentosa

Joseph F. Fowler, Jr, MD; William M. Parsley, MD; Pamela G. Cotter, MT(ASCP)
[+] Author Affiliations

Accepted for publication Sept 13, 1985.

Reprint requests to Division of Dermatology, School of Medicine, University of Louisville, 310 E Broadway, Louisville, KY 40292 (Dr Fowler).


From the Division of Dermatology, School of Medicine, University of Louisville.


Arch Dermatol. 1986;122(1):80-81. doi:10.1001/archderm.1986.01660130084031
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• Urticaria pigmentosa, characterized by cutaneous mast cell proliferation, usually occurs sporadically in childhood and resolves over a period. Rarely is the condition seen in two or more members of a family. We encountered a family in which urticaria pigmentosa occurred in four members of two generations. Skin findings were similar in all four. No systemic manifestations other than occasional flushing episodes were noted in any of the affected individuals. HLA typing was performed, but no significant correlation between affected and unaffected individuals was seen. In a review of a number of previously reported cases, we found a slight female preponderance.

(Arch Dermatol 1986;122:80-81)

REFERENCES

Staff, Transplantation and Immunology Branch: NIAD Manual of Tissue Typing Techniques . Los Angeles, UCLA Press, 1980;.
Atoub G, Terasaki PI:  Improved typing of cadaver donor by lymphocyte incubation . Tissue Antigens 1981;;18:1-10.
Bazex A, Dupro A, Christol B, et al:  Les mastocytoses familiales . Ann Dermatol 1971;;98:241-260.
Volovich LE:  Familial urticaria pigmentosa (Russian) . Vestn Dermatol Venerol 1966;;2:75.
Shaw JM:  Genetic aspects of urticaria pigmentosa . Arch Dermatol 1968;;97:137-138.
Klaber M:  Diffuse cutaneous mastocytosis in mother and daughter . Proc R Soc Med 1976;;69:16-18.
Rockoff AS:  Urticaria pigmentosa in identical twins . Arch Dermatol 1978;;114:1227-1228.
Aoki K, Suzuki H:  Urticaria pigmentosa in patients closely related by birth . J Dermatol 1981;;8:229-234.
Kuan YZ:  Urticaria pigmentosa in two pairs of monozygotic twins . J Dermatol 1980;;6:375-378.
Weber VK:  Urticaria Pigmentosa bei einigen Zwillingen . Dermatol Monatsschr 1973;;159:258-261.
Hufbauer M:  Klinische und therapeutische Kurzberichte über eine Familie mit Mastzellenerythrodermie . Hautarzt 1974;;25:246-249.
James MP, Eady RAJ:  Familial urticaria pigmentosa with giant mast cell granules . Arch Dermatol 1981;;117:713-718.
Gay MW, Noojin RO, Finley WH:  Urticaria pigmentosa discordant in identical twins . Arch Dermatol 1970;;102:29-33.
Selmanowitz VJ, Orentreich N, Tiangco CC, et al:  Uniovular twins discordant for cutaneous mastocytosis . Arch Dermatol 1970;;102:34-41.
Cainelli T, Marchesi L, Pasovali F, et al:  Monozygotic twins discordant for cutaneous mastocytosis . Arch Dermatol 1983;; 119:1021-1022.

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Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Staff, Transplantation and Immunology Branch: NIAD Manual of Tissue Typing Techniques . Los Angeles, UCLA Press, 1980;.
Atoub G, Terasaki PI:  Improved typing of cadaver donor by lymphocyte incubation . Tissue Antigens 1981;;18:1-10.
Bazex A, Dupro A, Christol B, et al:  Les mastocytoses familiales . Ann Dermatol 1971;;98:241-260.
Volovich LE:  Familial urticaria pigmentosa (Russian) . Vestn Dermatol Venerol 1966;;2:75.
Shaw JM:  Genetic aspects of urticaria pigmentosa . Arch Dermatol 1968;;97:137-138.
Klaber M:  Diffuse cutaneous mastocytosis in mother and daughter . Proc R Soc Med 1976;;69:16-18.
Rockoff AS:  Urticaria pigmentosa in identical twins . Arch Dermatol 1978;;114:1227-1228.
Aoki K, Suzuki H:  Urticaria pigmentosa in patients closely related by birth . J Dermatol 1981;;8:229-234.
Kuan YZ:  Urticaria pigmentosa in two pairs of monozygotic twins . J Dermatol 1980;;6:375-378.
Weber VK:  Urticaria Pigmentosa bei einigen Zwillingen . Dermatol Monatsschr 1973;;159:258-261.
Hufbauer M:  Klinische und therapeutische Kurzberichte über eine Familie mit Mastzellenerythrodermie . Hautarzt 1974;;25:246-249.
James MP, Eady RAJ:  Familial urticaria pigmentosa with giant mast cell granules . Arch Dermatol 1981;;117:713-718.
Gay MW, Noojin RO, Finley WH:  Urticaria pigmentosa discordant in identical twins . Arch Dermatol 1970;;102:29-33.
Selmanowitz VJ, Orentreich N, Tiangco CC, et al:  Uniovular twins discordant for cutaneous mastocytosis . Arch Dermatol 1970;;102:34-41.
Cainelli T, Marchesi L, Pasovali F, et al:  Monozygotic twins discordant for cutaneous mastocytosis . Arch Dermatol 1983;; 119:1021-1022.

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