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Dysplastic Epidermal Keratosis in a Black Woman

Sumala Lopansri, MD; A. Paul Kelly, MD; Seymour M. Weaver, MD
[+] Author Affiliations

Accepted for publication April 23, 1981.

Reprints not available.


From the Divisions of Dermatology (Drs Weaver and Kelly) and Dermatopathology (Dr Lopansri), Martin Luther King, Jr, General Hospital; and Charles R. Drew Postgraduate Medical School (Drs Kelly and Lopansri), Los Angeles.


Arch Dermatol. 1981;117(12):800-803. doi:10.1001/archderm.1981.01650120046021
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• Skin cancer is rare in black persons. When it does occur, in most cases it occurs on non-sun-exposed areas. In white persons, most skin cancer occurs in sites that have been exposed to sunlight for long periods. The decreased susceptibility of more darkly pigmented skin to the sequelae of long-term ultraviolet (UV)-energy exposure probably accounts for the low incidence of actinic keratoses, basal cell carcinomas, and squamous cell carcinomas in black persons. Multiple, dysplastic, epidermal lesions developed in a black woman, which were possibly induced by long-term UV-light or heat exposure. Her condition responded well to topical fluorouracil therapy but had an unusual delayed reaction to treatment.

(Arch Dermatol 1981;117:800-803)

REFERENCES

White JE, Strudwick WJ, Ricketts WN, et al:  Cancer of the skin in Negroes . JAMA 1961;;178:149-151.
Fleming ID, Barnwell JR, Burlison PE, et al:  Skin cancer in black patients . Cancer 1975;;35:600-605.
Amonette RA, Kaplan RJ:  Squamous cell and basal cell carcinoma in black patients . J Dermatol Surg Oncol 1976;;2:158-161.
Lever WF, Schaumburg-Lever G: Histopathology of the Skin . Philadelphia, JB Lippincott Co, 1975;, pp 16-20.
Arrington JH III, Lockman DS:  Thermal keratoses and squamous cell carcinoma in situ associated with erythema ab igne . Arch Dermatol 1979;;115:1226-1228.
Whitehead WJ, Moyer DG, Vander Ploeg DE:  Idiopathic guttate hypomelanosis . Arch Dermatol 1966;;94:279-281.
Wagner SL, Maliner JS, Morton WE, et al:  Skin cancer and arsenical intoxication from well water . Arch Dermatol 1979;;115:1205-1207.
Graham JH, Helwig EB:  Bowen's disease and its relationship to systemic cancer . Arch Dermatol 1961;;83:738-758.
Andersen SLC, Nielsen A, Reymann F:  Relationship between Bowen disease and internal malignant tumors . Arch Dermatol 1973;;108:367-370.
Callen JP, Headington J:  Bowen's and non-Bowen's squamous intraepidermal neoplasia of the skin: Relationship to internal malignancy . Arch Dermatol 1980;;116:422-426.
Limmer BL:  Bowen's disease: Treatment with topical 5-fluorouracil . Cutis 1975;;16:660-663.
Fulton JE Jr, Carter DM, Hurley HJ:  Treatment of Bowen's disease with topical 5-fluorouracil under occlusion . Arch Dermatol 1968;;97:178-180.
Simmonds WL:  Management of actinic keratosis with topical 5-fluorouracil . Cutis 1976;;18:298-300.
Goette DK, Odom RB, Owens R:  Allergic contact dermatitis from topical fluorouracil . Arch Dermatol 1977;;113;196-198.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

White JE, Strudwick WJ, Ricketts WN, et al:  Cancer of the skin in Negroes . JAMA 1961;;178:149-151.
Fleming ID, Barnwell JR, Burlison PE, et al:  Skin cancer in black patients . Cancer 1975;;35:600-605.
Amonette RA, Kaplan RJ:  Squamous cell and basal cell carcinoma in black patients . J Dermatol Surg Oncol 1976;;2:158-161.
Lever WF, Schaumburg-Lever G: Histopathology of the Skin . Philadelphia, JB Lippincott Co, 1975;, pp 16-20.
Arrington JH III, Lockman DS:  Thermal keratoses and squamous cell carcinoma in situ associated with erythema ab igne . Arch Dermatol 1979;;115:1226-1228.
Whitehead WJ, Moyer DG, Vander Ploeg DE:  Idiopathic guttate hypomelanosis . Arch Dermatol 1966;;94:279-281.
Wagner SL, Maliner JS, Morton WE, et al:  Skin cancer and arsenical intoxication from well water . Arch Dermatol 1979;;115:1205-1207.
Graham JH, Helwig EB:  Bowen's disease and its relationship to systemic cancer . Arch Dermatol 1961;;83:738-758.
Andersen SLC, Nielsen A, Reymann F:  Relationship between Bowen disease and internal malignant tumors . Arch Dermatol 1973;;108:367-370.
Callen JP, Headington J:  Bowen's and non-Bowen's squamous intraepidermal neoplasia of the skin: Relationship to internal malignancy . Arch Dermatol 1980;;116:422-426.
Limmer BL:  Bowen's disease: Treatment with topical 5-fluorouracil . Cutis 1975;;16:660-663.
Fulton JE Jr, Carter DM, Hurley HJ:  Treatment of Bowen's disease with topical 5-fluorouracil under occlusion . Arch Dermatol 1968;;97:178-180.
Simmonds WL:  Management of actinic keratosis with topical 5-fluorouracil . Cutis 1976;;18:298-300.
Goette DK, Odom RB, Owens R:  Allergic contact dermatitis from topical fluorouracil . Arch Dermatol 1977;;113;196-198.

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