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Article |

Hypopigmentation With Punctate Keratosis of the Palms and Soles

Maj Lonnie A. Cole, MC
[+] Author Affiliations

Accepted for publication April 30, 1975.

The opinions expressed are those of the author and not necessarily those of the US Air Force.

Reprints not available.


USAF

From the Dermatology Service, Wilford Hall US Air Force Medical Center, Lackland Air Force Base, Tex. Dr Cole is currently at McDill Regional Air Force Hospital, Tampa, Fla.


Arch Dermatol. 1976;112(7):998-1000. doi:10.1001/archderm.1976.01630310056013
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• Generalized discrete hypopigmented macules forming a camouflage pattern appeared on the skin of a man. The condition has been present and has not changed since the age of 6 months. Five other members of his family are reported to have the same abnormality. All affected members also have punctate keratosis of the palms and soles. An autosomal dominant pattern of inheritance is suggested.

(Arch Dermatol 112:998-1000, 1976)

REFERENCES

Suenga M:  Genetical studies on skin diseases: VII. Dyschromatosis universalis hereditaria in five generations . Tohoku J Exp Med 55:373-376, 1952;.
Moon-Adams D, Slatkin MH:  Familial pigmentation with dystrophy of the nails . Arch Dermatol 71:591-598, 1955;.
Wende GW, Bauckus HH:  A hitherto undescribed generalized pigmentation of the skin appearing in infancy in brother and sister . J Cutan Dis 37:685-700, 1919;.
Pegum JS:  Diffuse pigmentation in brothers . Proc R Soc Med 48:179-180, 1955;.
Berlin C:  Congenital generalized melanoleucoderma associated with hypodontia, hypotrichosis, stunted growth and mental retardation occurring in two brothers and two sisters . Dermatologica 123:227-243, 1961;.
Jost K:  Hereditare, connatole pigmentanomalie . Hautarzt 6:458-460, 1955;.
Flegel H:  Dermatopathia pigmentosa reticularis . Hautarzt 11:262-265, 1960;.
Oakley DE:  Generalized macular pigmentation . Br J Dermatol 60:108, 1948;.
Demis DJ, Crounse RG, Dobson RL, et al: Clinical Dermatology . Hagerstown, Md, Harper & Row Publishers, 1974;.
Bean SF, Foxley EG, Fusaro RM:  Palmar keratoses and internal malignancy . Arch Dermatol 97:528-532, 1968;.
Dobson RL, Young MR, Pinto JS:  Palmar keratoses and cancer . Arch Dermatol 92:553-556, 1965;.
Stolman LP, Kopf AW, Garfinkel L:  Are palmar keratoses a sign of internal malignancy? Arch Dermatol 101:52-55, 1970;.
Whimster IW:  An experimental approach to the problem of spottiness . Br J Dermatol 77:397-420, 1965;.

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Suenga M:  Genetical studies on skin diseases: VII. Dyschromatosis universalis hereditaria in five generations . Tohoku J Exp Med 55:373-376, 1952;.
Moon-Adams D, Slatkin MH:  Familial pigmentation with dystrophy of the nails . Arch Dermatol 71:591-598, 1955;.
Wende GW, Bauckus HH:  A hitherto undescribed generalized pigmentation of the skin appearing in infancy in brother and sister . J Cutan Dis 37:685-700, 1919;.
Pegum JS:  Diffuse pigmentation in brothers . Proc R Soc Med 48:179-180, 1955;.
Berlin C:  Congenital generalized melanoleucoderma associated with hypodontia, hypotrichosis, stunted growth and mental retardation occurring in two brothers and two sisters . Dermatologica 123:227-243, 1961;.
Jost K:  Hereditare, connatole pigmentanomalie . Hautarzt 6:458-460, 1955;.
Flegel H:  Dermatopathia pigmentosa reticularis . Hautarzt 11:262-265, 1960;.
Oakley DE:  Generalized macular pigmentation . Br J Dermatol 60:108, 1948;.
Demis DJ, Crounse RG, Dobson RL, et al: Clinical Dermatology . Hagerstown, Md, Harper & Row Publishers, 1974;.
Bean SF, Foxley EG, Fusaro RM:  Palmar keratoses and internal malignancy . Arch Dermatol 97:528-532, 1968;.
Dobson RL, Young MR, Pinto JS:  Palmar keratoses and cancer . Arch Dermatol 92:553-556, 1965;.
Stolman LP, Kopf AW, Garfinkel L:  Are palmar keratoses a sign of internal malignancy? Arch Dermatol 101:52-55, 1970;.
Whimster IW:  An experimental approach to the problem of spottiness . Br J Dermatol 77:397-420, 1965;.

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