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The Enigma of Bullous Pemphigoid and Dermatitis Herpetiformis

Juan F. Honeyman, MD; Ana Honeyman, MT; Walter C. Lobitz, Jr., MD; Frances J. Storrs, MD
[+] Author Affiliations

Accepted for publication Sept 14, 1971.

Reprint requests to Department of Dermatology, University of Oregon Medical School, Portland 97201 (Dr. Lobitz).


Portland, Ore

From the Department of Dermatology, University of Oregon Medical School, Portland. Dr. Honeyman is a W. K. Kellog Foundation Fellow (Dermatology) from the University of Chile Medical School, Santiago. Ana Honeyman is a visiting research associate from the University of Chile Medical School.


Arch Dermatol. 1972;106(1):22-25. doi:10.1001/archderm.1972.01620100010002
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We describe five patients who share clinical, histopathological, therapeutic response, and immunofluorescence criteria for both dermatitis herpetiformis and pemphigoid. Furthermore, one patient who was studied over a period of time changed from fulfilling all the criteria of dermatitis herpetiformis to those of bullous pemphigoid.

REFERENCES

Rook A, Wilkinson DS, Ebling FJ: Textbook of Dermatology . Philadelphia, Blackwell Scientific Publications, 1968;.
Fitzpatrick TB, Arndt KA, Clark WH, et al: Dermatology in General Medicine . New York, McGraw-Hill Book Co Inc, 1971;.
Lever WF: Pemphigus and Pemphigoid . Springfield, Ill, Charles C Thomas Publisher, 1965;.
Demis JD, Crounse RG, Dobson RL, et al: Clinical Dermatology . New York, Harper & Row Publishers Inc, to be published.
Tolman MM, Moschella SL, Schneiderman RH:  Dermatitis herpetiformis: Specific entity or clinical complex? J Invest Derm 32:551-561, 1959;.
Van der Meer JB:  Granular deposits of immunoglobulins in the skin of patients with dermatitis herpetiformis: An immunofluorescent study . Brit J Derm 81:493-503, 1969;.
Chorzelski TP, Beutner EH, Jablonska S, et al:  Immunofluorescence studies in the diagnosis of dermatitis herpetiformis and its differentiation from bullous pemphigoid . J Invest Derm 56:373-380, 1971;.
Lever WF: Histopathology of the Skin . Philadelphia, JB Lippincott Co, 1967;.
Pierard J, Whimster I:  The histological diagnosis of dermatitis herpetiformis, bullous pemphigoid and erythema multiforme . Brit J Derm 73:253-266, 1961;.
Beutner EH, Chorzelski TP, Jordon RE: Autosensitization in Pemphigus and Bullous Pemphigoid . Springfield, Ill, Charles C Thomas Publisher, 1970;.
Chorzelski TP, Jablonska S, Blaszcyk M, et al:  Autoantibodies in pemphigoid . Dermatologica 136:325-334, 1968;.
Sams WM Jr:  Bullous pemphigoid . Arch Derm 102:485-497, 1970;
Cormane RH, Szabo E:  Immuno-histopathology of the skin in pemphigoid . Brit J Derm 83:435-445, 1970;.
Cormane RH, Szabo E, Hauge LS:  Immunofluorescence of the skin: The interpretation of the staining of blood vessels and connective tissue aided by new techniques . Brit J Derm 82 ( (suppl 5) ):26-43, 1970;.
Beutner EH, Jordon RE, Chorzelski TP:  The immunopathology of pemphigus and bullous pemphigoid . J Invest Derm 51:63-80, 1968;.
Duhring L:  Dermatitis herpetiformis . JAMA 3:225-229, 1884;.
Lever WF:  Pemphigus . Medicine 32:1-123, 1953;.
Jablonska S:  Duhring's disease and pemphigoid: Milestones in dermatology . Excerpta Med Derm 18:245-247, 1964;.
Thivolet J, Beyvin AJ, Perrot H, et al:  Auto-immunite au cours de la maladie de Duhring-Brocq . Bull Soc Franc Derm Syph 76/ (3) :463-467, 1969;.

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Rook A, Wilkinson DS, Ebling FJ: Textbook of Dermatology . Philadelphia, Blackwell Scientific Publications, 1968;.
Fitzpatrick TB, Arndt KA, Clark WH, et al: Dermatology in General Medicine . New York, McGraw-Hill Book Co Inc, 1971;.
Lever WF: Pemphigus and Pemphigoid . Springfield, Ill, Charles C Thomas Publisher, 1965;.
Demis JD, Crounse RG, Dobson RL, et al: Clinical Dermatology . New York, Harper & Row Publishers Inc, to be published.
Tolman MM, Moschella SL, Schneiderman RH:  Dermatitis herpetiformis: Specific entity or clinical complex? J Invest Derm 32:551-561, 1959;.
Van der Meer JB:  Granular deposits of immunoglobulins in the skin of patients with dermatitis herpetiformis: An immunofluorescent study . Brit J Derm 81:493-503, 1969;.
Chorzelski TP, Beutner EH, Jablonska S, et al:  Immunofluorescence studies in the diagnosis of dermatitis herpetiformis and its differentiation from bullous pemphigoid . J Invest Derm 56:373-380, 1971;.
Lever WF: Histopathology of the Skin . Philadelphia, JB Lippincott Co, 1967;.
Pierard J, Whimster I:  The histological diagnosis of dermatitis herpetiformis, bullous pemphigoid and erythema multiforme . Brit J Derm 73:253-266, 1961;.
Beutner EH, Chorzelski TP, Jordon RE: Autosensitization in Pemphigus and Bullous Pemphigoid . Springfield, Ill, Charles C Thomas Publisher, 1970;.
Chorzelski TP, Jablonska S, Blaszcyk M, et al:  Autoantibodies in pemphigoid . Dermatologica 136:325-334, 1968;.
Sams WM Jr:  Bullous pemphigoid . Arch Derm 102:485-497, 1970;
Cormane RH, Szabo E:  Immuno-histopathology of the skin in pemphigoid . Brit J Derm 83:435-445, 1970;.
Cormane RH, Szabo E, Hauge LS:  Immunofluorescence of the skin: The interpretation of the staining of blood vessels and connective tissue aided by new techniques . Brit J Derm 82 ( (suppl 5) ):26-43, 1970;.
Beutner EH, Jordon RE, Chorzelski TP:  The immunopathology of pemphigus and bullous pemphigoid . J Invest Derm 51:63-80, 1968;.
Duhring L:  Dermatitis herpetiformis . JAMA 3:225-229, 1884;.
Lever WF:  Pemphigus . Medicine 32:1-123, 1953;.
Jablonska S:  Duhring's disease and pemphigoid: Milestones in dermatology . Excerpta Med Derm 18:245-247, 1964;.
Thivolet J, Beyvin AJ, Perrot H, et al:  Auto-immunite au cours de la maladie de Duhring-Brocq . Bull Soc Franc Derm Syph 76/ (3) :463-467, 1969;.

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