Correspondence |

Septic Facial Vein Thrombosis Due to Panton-Valentine Leukocidin–Positive Staphylococcus aureus

Norah Kramkimel, MD; Emilie Sbidian, MD; Tu Anh Duong, MD; Philippe Lesprit, MD; Jean-Claude Roujeau, PhD, MD; Martine Bagot, PhD, MD
Arch Dermatol. 2009;145(12):1460-1461. doi:10.1001/archdermatol.2009.317.
Text Size: A A A
Published online


Facial malignant staphylococcal infection is a rare infectious disorder characterized by a septic facial venous thrombosis. Herein we report the first case to our knowledge in a healthy young woman due to Panton-Valentine leukocidin (PVL)–positive Staphylococcus aureus.

Ayadi  KMehdi  MKhannous  M  et al Septic thrombosis of the cavernous sinus complicating malignant staphylococcal infection of the face. J Radiol1995768497499
Gillet  YIssartel  BVanhems  P  et al Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet20023599308753759
Holmes  AGanner  M McGuane  SPitt  TLCookson  BDKearns  AM Staphylococcus aureus isolates carrying Panton-Valentine leucocidin genes in England and Wales: frequency, characterization, and association with clinical disease. J Clin Microbiol200543523842390
Sinha  BHerrmann  M Mechanism and consequences of invasion of endothelial cells by Staphylococcus aureusThromb Haemost2005942266277
Figures in this Article

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview


Place holder to copy figure label and caption

Figure 1. Marked facial edema with predominance about the periorbital region, especially of the right eye (A) and total recovery after treatment (B).

Graphic Jump Location
Place holder to copy figure label and caption

Figure 2. Computed tomography images. A and B, Important infiltration of facial soft tissues and filling defects of the bilateral facial veins (arrow). C, Filling defects of the right superior ophthalmic vein (left arrow); the left superior ophthalmic vein is permeable (right arrow).

Graphic Jump Location




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics