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Correspondence |

An Association of Idiopathic Chronic Eosinophilic Pneumonia With Pemphigoid Nodularis: A Rare Variant of Bullous Pemphigoid

Hiroshi Koga, MD; Takahiro Hamada, MD; Bungo Ohyama, MD; Takekuni Nakama, MD; Shinichiro Yasumoto, MD; Takashi Hashimoto, MD
Arch Dermatol. 2009;145(11):1339-1340. doi:10.1001/archdermatol.2009.273.
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Powell  AMAlbert  SGratian  MJBittencourt  RBhogal  BSBlack  MM Pemphigoid nodularis (non-bullous): a clinicopathological study of five cases. Br J Dermatol 2002;147 (2) 343- 349
PubMed Link to Article[[XSLOpenURL/10.1046/j.1365-2133.2002.04754.x]]
Tsuda  SMiyasato  MIryo  KNakama  TKato  KSasai  Y Eosinophil phenotypes in bullous pemphigoid. J Dermatol 1992;19 (5) 270- 279
Saitoh  KShindo  NToh  YYoshizawa  AKudo  K Electron microscopic study of chronic eosinophilic pneumonia. Pathol Int 1996;46 (11) 855- 861
PubMed Link to Article[[XSLOpenURL/10.1111/pin.1996.46.issue-11]]
Gounni Abdeliah  SWellemans  VAgouli  M  et al.  Increased expression of Th2-associated chemokines in bullous pemphigoid disease: role of eosinophils in the production and release of these chemokines. Clin Immunol 2006;120 (2) 220- 231
PubMed Link to Article[[XSLOpenURL/10.1016/j.clim.2006.03.014]]
Tateno  HNakamura  HMinematsu  N  et al.  Eotaxin and monocyte chemoattractant protein-1 in chronic eosinophilic pneumonia. Eur Respir J 2001;17 (5) 962- 968
PubMed Link to Article[[XSLOpenURL/10.1183/09031936.01.17509620]]
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Figure 1

Prurigo nodularis–like lesions are present on the lower limb (A), and a bulla and erosion are found on the forearm (B).

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Figure 2

Immunohistopathologic studies. A, Hematoxylin-eosin staining under light microscopy reveals irregular acanthosis with pseudoepitheliomatous hyperplasia (original magnification ×40); the inset shows an infiltration of many lymphocytes and a few eosinophils in the upper dermis (original magnification ×200). B, Direct immunofluorescence demonstrates linear deposits of IgG at the basement membrane zone of the epidermis (original magnification ×200).

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