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Correspondence | October 2009

Acute Edema/Cutaneous Distention Syndrome Associated With Refeeding in a Patient With Anorexia Nervosa

Mari Kishibe, MD, PhD; Hiroyuki Sakai, MD, PhD; Hajime Iizuka, MD, PhD

Arch Dermatol. 2009;145(10):1202-1203. doi:10.1001/archdermatol.2009.240.

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We herein report a case of acute edema/cutaneous distention syndrome (AECDS) triggered by refeeding in a patient with anorexia nervosa. Patients with anorexia nervosa should be carefully monitored because nutritional therapy may induce AECDS.

Cox NHChalmers RJBhushan M The acute edema/cutaneous distension syndrome. Arch Dermatol 2003;139 (2) 224- 225
PubMed

Bhushan MChalmers RJCox NH Acute oedema blisters: a report of 13 cases. Br J Dermatol 2001;144 (3) 580- 582
PubMed

Bhushan MCox NHChalmers RJ Eczéma craquelé resulting from acute oedema. Br J Dermatol 2001;145 (2) 355- 357
PubMed

Ishiguro NHirohara DHotta MTakano KKawashima M Linear erythéma craquelé due to acute oedema in anorexia nervosa. Br J Dermatol 2001;145 (2) 357- 359
PubMed

Ishiguro NKawashima M Striaelike epidermal distension: a newly recognized cutaneous manifestation in acute leg edema. Arch Dermatol 2002;138 (5) 641- 642
PubMed

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Lesions on the leg of our patient. A, Linear erythematous lesions, grayish bullae, and edema were seen on admission. B, Worsening of the linear erosions, erythema, and grayish bullae were noted 4 days after refeeding.

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Histopathologic analysis showed necrotic keratinocytes in the upper layers and spongiosis in the lower layers of the epidermis. Edema, dilated blood vessels, and extravasated erythrocytes are present in the underlying dermis.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Kishibe M, Sakai H, Iizuka H, Kishibe M, Sakai H, Iizuka H. Acute Edema/Cutaneous Distention Syndrome Associated With Refeeding in a Patient With Anorexia Nervosa. Arch Dermatol. 2009;145(10):1202-1203. doi:10.1001/archdermatol.2009.240.

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