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Correspondence |

Acute Generalized Exanthematous Pustulosis Associated With Asymptomatic Mycoplasma pneumoniae Infection

Christopher Seng-Hong Lim, MBBS; Siew-Lin Lim, MBBS
Arch Dermatol. 2009;145(7):848-849. doi:10.1001/archdermatol.2009.127.
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Acute generalized exanthematous pustulosis (AGEP) is most commonly associated with drug hypersensitivity.1 Infections are an uncommon cause, and most known infectious causes have been viral.2 We know of only a single case of AGEP associated with Chlamydia pneumoniae infection.3 Herein, we report a case of AGEP in an adult following asymptomatic Mycoplasma pneumoniae infection.

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Figure 1.

Erythematous maculopapular eruption with nonfollicular pustules becoming confluent and forming superficial lakes of pus in the right axilla.

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Figure 2.

Subcorneal spongiform pustule with adjacent spongiosis and papillary dermal edema and a superficial perivascular infiltrate of lymphocytes, histiocytes, and a few eosinophils. Red blood cell extravasation is also present but no necrotizing vasculitis (hematoxylin-eosin, original magnification ×400).

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