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Correspondence |

Relapsing Leukocytoclastic Vasculitis Triggered by Activity in a Young Woman

Amit Garg, MD; Dori Goldberg, MD
Arch Dermatol. 2009;145(5):601-602. doi:10.1001/archdermatol.2009.66.
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Among the challenges of the protean disorder leukocytoclastic vasculitis is discovering its cause. The occurrence of leukocytoclastic vasculitis in response to activity is an uncommonly recognized association. We highlight the association of physical activity with cutaneous small-vessel vasculitis and suggest that activity also be considered as a cause of leukocytoclastic vasculitis.

Ramelet  AA Exercise-induced vasculitis. J Eur Acad Dermatol Venereol 2006;20 (4) 423- 427
PubMed Link to Article[[XSLOpenURL/10.1111/jdv.2006.20.issue-4]]
Kelly  RIOpie  JNixon  R Golfer's vasculitis. Australas J Dermatol 2005;46 (1) 11- 14
PubMed Link to Article[[XSLOpenURL/10.1111/ajd.2005.46.issue-1]]
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Figure 1.

Purpuric plaques on the lower extremities during an activity-induced flare. The inset shows purpuric plaques with central and peripheral clearing imparting crescent and gyrate shapes and with a peripheral rim of pallor.

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Figure 2.

Histopathologic specimens taken from our patient's lesion. The primary image demonstrates both superficial and deep perivascular inflammation (hematoxylin-eosin, original magnification ×4). The inset shows leukocytoclasia, fibrinoid necrosis of vessel walls, and red blood cell extravasation (hematoxylin-eosin, original magnification ×40).

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