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Correspondence |

Blepharochalasis: A Rare Condition Misdiagnosed as Recurrent Angioedema

Gang Wang, MD, PhD; Chunying Li, MD, PhD; Tianwen Gao, MD, PhD
Arch Dermatol. 2009;145(4):498-499. doi:10.1001/archdermatol.2009.19.
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Blepharochalasis is an uncommon condition occurring in young people at about the time of puberty. It is characterized by recurrent episodes of nonpitting, nonpainful, nonerythematous edema on the upper eyelids that leaves wrinkled, redundant, and thinned eyelid skin and results in atrophy and relaxation of the eyelid structures and ptosis.1 Blepharochalasis, especially in its early stage, is easily misdiagnosed as angioedema.24

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Clinical (A) and histopathologic (B and C) images from the subject case. A, Bilateral upper eyelid laxity with edema and ptosis of eyelids. B, Minor perivascular lymphocytic infiltrate (hematoxylin-eosin, original magnification ×10). C, Short and fragmented elastic fibers (Verhoeff-van Gieson stain, original magnification ×20).

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