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Correspondence |

HAIR-AN Syndrome in a Male Adolescent With Concomitant Vitiligo

Zhu Shen, MD, PhD; Fei Hao, MD, PhD; Ping Wei, MD, PhD
Arch Dermatol. 2009;145(4):492-494. doi:10.1001/archdermatol.2009.12.
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HAIR-AN syndrome is an unusual multisystem disorder that consists of hyperandrogenism, insulin resistance, and acanthosis nigricans. Specific skin disorders often appear in association with hyposecretion or hypersecretion from the endocrine glands. Knowledge of skin alterations is valuable not only for dermatologists but also for other physicians because a clinical diagnosis of the underlying disease is often possible based on these alterations.1 Herein, we report an unusual skin presentation of HAIR-AN syndrome with concomitant vitiligo in a 16-year-old male adolescent.

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Figure 1.

Hyperpigmented, velvety patches of acanthosis nigricans on the neck (A), back sides of the joints (B), axillae (C), and perianal region (D). The concomitant vitiligo was seen on the backs of hands (B) and perianal region (D).

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Figure 2.

Concomitant vitiligo was also found on the occipitoposterior scalp.

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