Correspondence |

Type 1 Leprosy Reaction Manifesting After Discontinuation of Adalimumab Therapy

Ivan D. Camacho, MD; Isabel Valencia, MD; Maria P. Rivas, MD; Anne E. Burdick, MD, MPH
Arch Dermatol. 2009;145(3):349-351. doi:10.1001/archdermatol.2009.10.
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Lee  HHSong  IHFriedrich  M  et al.  Cutaneous side-effects in patients with rheumatic diseases during application of tumour necrosis factor-alpha antagonists. Br J Dermatol 2007;156 (3) 486- 491
Desai  SBFurst  DE Problems encountered during anti-tumour necrosis factor therapy. Best Pract Res Clin Rheumatol 2006;20 (4) 757- 790
Scollard  DMJoyce  MPGillis  TP Development of leprosy and type 1 leprosy reactions after treatment with infliximab: a report of 2 cases. Clin Infect Dis 2006;43 (2) e19- e22
Deps  PDGripp  CGMadureira  BPLucas  EA Immune reconstitution syndrome associated with leprosy: two cases. Int J STD AIDS 2008;19 (2) 135- 136
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Figure 1

Clinical appearance of our patient. A, Erythematous and edematous right ear. B, Erythematous papules and plaques on the chest.

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Figure 2

The primary image shows diffuse granulomatous infiltrate (hematoxylin-eosin, original magnification ×40), and the inset shows scattered acid-fast bacilli (arrows) (Fite stain, original magnification ×100).

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