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Docetaxel Monotherapy for Angiosarcoma in an Elderly Patient

Tohru Nagano, MD, PhD; Yukimasa Tai, MD; Yuka Higashida, MD; Norihiro Fujiwara, MD; Masahiro Oka, MD, PhD; Chikako Nishigori, MD, PhD
Arch Dermatol. 2007;143(12):1589-1603. doi:10.1001/archderm.143.12.1602.
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Treatment of angiosarcoma (AS) of the scalp in elderly patients remains difficult owing to the high frequency of local recurrence and lung metastasis.1 Recently, weekly low-dose docetaxel therapy has proven effective for treating local recurrences and lung metastases of AS of the scalp2,3 and radiation-induced AS of the breast.4 Herein, we describe a patient with AS of the scalp and face treated with docetaxel alone who showed a partial response.

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Figure 1.

Clinical appearance before treatment with docetaxel. Facial edema and widespread violaceous plaques with disseminated dark purple nodules were seen on her cheek with extension to the mandible.

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Figure 2.

Clinical appearance 8 weeks after beginning weekly docetaxel regimen.

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