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Correspondence |

Bleomycin-Induced “Flagellate Dermatitis”

Gehan Arseculeratne, MRCP; Laura Berroeta, MRCP; David Meiklejohn, MD, MRCPEd, MRCPath; Rodney E. Mountain, FRCS(ORL)Ed; Jamie C. Ryan, FRACS; Catherine Spinou, MRCSEd; Sachi N. Das, FRCR, DMRT; Alan T. Evans, MD, FRCPath; J. Graham Lowe, FRCP
Arch Dermatol. 2007;143(11):1447-1462. doi:10.1001/archderm.143.11.1461.
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Umezawa  H Bleomycin and other antitumor antibiotics of high molecular weight. Antimicrobial Agents Chemother (Bethesda) 1965;51079- 1085
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Mowad  CMNguyen  TVElenitsas  R  et al.  Bleomycin-induced flagellate dermatitis: a clinical and histopathological review. Br J Dermatol 1994;131 (5) 700- 702
PubMed Link to Article[[XSLOpenURL/10.1111/bjd.1994.131.issue-5]]
Mak  RKWakelin  SH Shiitake dermatitis: the first case reported from a European country. Br J Dermatol 2006;154 (4) 800- 801
PubMed Link to Article[[XSLOpenURL/10.1111/bjd.2006.154.issue-4]]
Perrot  HOrtonne  JP Hyperpigmentation after bleomycin therapy: ultrastructural study. Arch Dermatol Res 1978;261 (3) 245- 252
PubMed Link to Article[[XSLOpenURL/10.1007/BF00455292]]
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Figure 1.

Bleomycin-induced flagellate dermatitis manifesting as multiple, erythematous, indurated, linear lesions on the left shoulder.

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Figure 2.

Histopathologic appearance of flagellate dermatitis. Perivascular cuffing of a small dermal blood vessel, a dilated lymphatic vessel, and many eosinophils in the interstitial space, some showing degranulation (arrow) (hematoxylin-eosin, original magnification ×200).

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