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Skin Cancer Presenting as a Nonhealing Wound: The Association of Polio and Skin Cancer

Jenny Vu, MD; Scott Bangert, MD; Adelaide A. Hebert, MD
Arch Dermatol. 2007;143(10):1331-1344. doi:10.1001/archderm.143.10.1338-b.
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Survivors of polio epidemics from the 1940s and 1950s make up a significant proportion of the US patient population. In addition to morbidity secondary to paralytic polio and postpolio syndrome, an association with malignant neoplasm has been proposed.1 We present a case of skin cancers arising in a patient with polio to further strengthen this possible association.

Nielsen  NMWohlfahrt  JAaby  P  et al.  Cancer risk in a cohort of polio patients. Int J Cancer 2001;92 (4) 605- 608
PubMed Link to Article[[XSLOpenURL/10.1002/(ISSN)1097-0215]]
Farbu  EGilhus  NEBarnes  MP  et al.  EFNS guideline on diagnosis and management of post-polio syndrome: report of an EFNS taskforce. Eur J Neurol 2006;13 (8) 795- 801
PubMed Link to Article[[XSLOpenURL/10.1111/ene.2006.13.issue-8]]
Gawne  ACHalstead  LS Postpolio syndrome: pathophysiology and clinical management. Crit Rev Phys Med Rehab 1995;7147- 188
Basson  MDBurney  RE Defective wound healing in patients with paraplegia and quadriplegia. Surg Gynecol Obstet 1982;155 (1) 9- 12
Kirsner  RSSpencer  JFalanga  VGarland  LEKerdel  FA Squamous cell carcinoma arising in osteomyelitis and chronic wounds: treatment with Mohs micrographic surgery vs. amputation. Dermatol Surg 1996;22 (12) 1015- 1018
PubMed Link to Article[[XSLOpenURL/10.1111/j.1524-4725.1996.tb00654.x]]
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Figure 1.

A 2.5 × 3.5-cm ulcer on the right anterior shin.

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Figure 2.

Basal cell carcinoma with sclerotic features.

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