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Correspondence |

Leukemia Cutis: A Presenting Sign in Acute Promyelocytic Leukemia

Tania R. Markowski, BA; Donna Bilu Martin, MD; Grace F. Kao, MD; Linda Lutz, MD; April Deng, MD, PhD; Anthony A. Gaspari, MD
Arch Dermatol. 2007;143(9):1209-1226. doi:10.1001/archderm.143.9.1220.
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Gambichler  THerde  MHoffmann  KAltmeyer  PJansen  T Poor prognosis of acute myeloid leukemia associated with leukemia cutis. J Eur Acad Dermatol Venereol 2002;16 (2) 177- 188
PubMed Link to Article[[XSLOpenURL/10.1046/j.1468-3083.2002.00392_5.x]]
Löwenberg  BGriffin  JDTallman  MS Acute myeloid leukemia and acute promyelocytic leukemia. Hematology Am Soc Hematol Educ Program 2003;82- 101
Giralt  SO’Brian  SWeeks  E  et al.  Leukemia cutis in acute promyelocytic leukemia: reports of three cases after treatment with all-trans retinoic acid. Leuk Lymphoma 1994;14 (5-6) 453- 456
PubMed Link to Article[[XSLOpenURL/10.3109/10428199409049703]]
Ratnam  KVKhor  CJLSu  WPD Leukemia cutis. Dermatol Clin 1994;12 (2) 419- 431
PubMed Link to Article[[XSLOpenURL/10.1016/0738-081X(94)90294-1]]
Ueda  KKume  AFurukawa  YHigashi  N Cutaneous infiltration in acute promyelocytic leukemia. J Am Acad Dermatol 1997;36 (1) 104- 106
PubMed Link to Article[[XSLOpenURL/10.1016/S0190-9622(97)70337-2]]
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Figure 1.

Three erythematous, nontender, indurated plaques with necrotic centers ranging in size from 5 to 9 mm were present on the patient's left calf.

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Figure 2.

In a biopsy specimen taken from a lesion on the patient's calf, immature hematopoietic cells stained diffusely positive for chloracetic esterase by Leder stain (original magnification ×40).

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