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Correspondence |

Nocardia otitidiscaviarum: Cause of Long-term Cutaneous Abscesses on the Leg of an Immunocompetent Man

Kai-Martin Thoms, MD; Ortrud Zimmermann, Dipl-Biol; Peter Schupp, MD; Sabine Thoms, MD; Steffen Emmert, MD
Arch Dermatol. 2007;143(8):1073-1087. doi:10.1001/archderm.143.8.1086.
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Hachisuka  HIchiki  MYoshida  NNakano  SSasai  Y Primary subcutaneous abscess caused by Nocardia otitidiscaviarumJ Am Acad Dermatol 1989;21 (1) 137- 139
PubMed Link to Article[[XSLOpenURL/10.1016/S0190-9622(89)80355-X]]
Freland  CFur  JLNemirovsky-Trebucq  BLelong  PBoiron  P Primary cutaneous nocardiosis caused by Nocardia otitidiscaviarum: two cases and a review of the literature. J Trop Med Hyg 1995;98 (6) 395- 403
Brown-Elliott  BABrown  JMConville  PSWallace  RJ  Jr Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomy. Clin Microbiol Rev 2006;19 (2) 259- 282
PubMed Link to Article[[XSLOpenURL/10.1128/CMR.19.2.259-282.2006]]
Schaal  KPLee  HJ Actinomycete infections in humans: a review. Gene 1992;115 (1-2) 201- 211
PubMed Link to Article[[XSLOpenURL/10.1016/0378-1119(92)90560-C]]
Wlodaver  CGTolomeo  TBenear  JB Primary cutaneous nocardiosis mimicking sporotrichosis. Arch Dermatol 1988;124 (5) 659- 660
PubMed Link to Article[[XSLOpenURL/10.1001/archderm.1988.01670050017009]]
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Figure 1.

Inflammatory nodules, fistulas, and abscesses on the left leg. A, Overview; B, detail. Cessation of inflammation, purulent secretion (C), and scarred healing of abscesses with postinflammatory hyperpigmentation (D) after a 4-week treatment regimen with imipenem and amikacin.

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Figure 2.

Lesional skin biopsy specimen with unspecific nodular inflammatory infiltrates in the middle of the dermis. The inflammatory nodules contain a polymorphic cellular infiltrate with microabscesses surrounded by eosinophilic granulocytes, histiocytes, and plasma cells (hematoxylin-eosin, original magnification ×400).

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Figure 3.

Columbia blood agar containing rough, cerebriform, brownish-orange Nocardia otitidiscaviarum colonies (A); the chalky-white color indicates aerial hyphae generated by the bacteria (B).

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