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Fox-Fordyce Disease Treated With Topical Clindamycin Solution

Matthew L. Miller, MC; Robert R. Harford, MC; Josef K. Yeager, MC
Arch Dermatol. 1995;131(10):1112-1113. doi:10.1001/archderm.1995.01690220018003.
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REPORT OF A CASE  A 32-year-old African-American woman presented to our clinic complaining of an extremely pruritic, burning rash in both axillae. The patient reported that the rash was worse in the summer and could be exacerbated by exercise or by activities that caused sweating. The patient denied any involvement in the areas of the groin or nipple. The eruption began at age 19 years but had remitted throughout the years on the administration of oral contraceptives and when the patient had become pregnant. On presentation, the patient had been suffering from her rash for the 2 years since the birth of her last child. Of interest, a sister also suffered from the same rash.On physical examination, the patient was noted to have discrete, flesh-colored perifollicular papules in the axillary vaults bilaterally (Figure 1). The areolae and groin were normal.A punch biopsy specimen of one of the papules


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