Article |

Eosinophilia-Myalgia Syndrome and L-Tryptophan-Containing Products—New Mexico, Minnesota, Oregon, and New York, 1989

Arch Dermatol. 1990;126(2):152-153. doi:10.1001/archderm.1990.01670260022002.
Text Size: A A A
Published online

As of November 21, 360 cases of eosinophilia-myalgia syndrome (EMS) had been reported by state health departments to CDC. Studies examining an association of L-tryptophan-containing products (LTCPs) with the EMS epidemic1 have been completed in New Mexico, Minnesota, and Oregon. In addition, a fatal case in New York has been reported.

New Mexico  In a New Mexico casecontrol study, EMS cases (N = 12) were all persons for whom an eosinophil count of 2000 cells/mm3 was recorded from May 1 through November 11, 1989, in nine laboratories in Albuquerque, Santa Fe, and Los Alamos and for whom incapacitating myalgia was documented, either in the medical record or by interview with the patient. Potential cases were excluded if eosinophilia could have been caused by any of a predetermined list of approximately 20 infectious, neoplastic, allergic, or other chronic diseases. EMS cases were compared with controls (two per case) who had been


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.