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Histologic Variation of a Pilomatrixoma

Akinobu Shoji, MD; Toshio Hamada, MD
Arch Dermatol. 1983;119(10):793-794. doi:10.1001/archderm.1983.01650340003008.
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To the Editor.—  Pilomatrixoma is a tumor usually located in the dermis and composed of sharply demarcated, round cellular islands, producing a lobulated contour. Of the more than 1,500 cases reported in the literature, approximately 96% of the patients had solitary lesions. After reviewing the available literature, Moehlenbeck1 deduced that the incidence of multiple pilomatrixoma was 3.5%. However, there were no cases of histopathologically established multicentric pilomatrixoma contained in one clinical lesion.

Report of a Case.—  A healthy 27-year-old man had a tender and slightly pruritic lump on the upper lateral aspect of his left arm develop in 1974. The lesion ulcerated spontaneously and was treated with acriflavine-soaked gauze by his physician. Two years later, when the patient was first seen by us at the dermatology, clinic, a firm nodule that was erythematous peripherally and eroded centrally, developed on the upper lateral aspect of his left arm. The tumor

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