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Netherton's Syndrome and Ichthyosis Linearis Circumflexa:  Psoriasiform Ichthosis

Jules Altman, MD; James Stroud, MD
Arch Dermatol. 1969;100(5):550-558. doi:10.1001/archderm.1969.01610290034007.
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Two patients with typical features of both ichthyosis linearis circumflexa and Netherton's syndrome are reported. Although these two rare variants of ichthyosis have previously been considered to be distinct, they actually appear to be the same entity manifesting as a peculiar defect in keratinization affecting the skin and hair.

The term "psoriasiform ichthyosis" is proposed to include ichthyosis linearis circumflexa-Netherton's syndrome, and perhaps other variants of ichthyosis with psoriasiform features which do not appear to fit into the existing classification of ichthyosiform dermatoses.

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