Five male patients with atrophic striae in the groins are reported. All patients received Mycolog cream* topically. None received corticosteroids orally or parenterally. No corticotropin was given. Current theories of the mechanism of the production of striae are discussed. We suggest that the initial change is nonunion of groups of connective tissue fibrils. This is most clearly demonstrated for elastic tissue.
The possibility is raised that local inflammation and topically applied corticosteroids may influence the production of striae. The serious consequences of striae are mentioned. Caution is advised in the use of corticosteroids in the treatment of intertrigo.