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Some Unusual Allergic Reactions in Industry

MARCUS M. KEY, M.D.
Arch Dermatol. 1961;83(1):3-6. doi:10.1001/archderm.1961.01580070009002.
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The allergic reaction in industry of most interest to the dermatologist is allergic contact dermatitis, which accounts for 20% or less of all occupationally incurred contact dermatitis. Other forms of industrial allergy are uncommon to rare, but the dermatologist may also see some cases of bronchial asthma and urticaria caused by certain agents in the occupational environment. This review of allergens in industry is designed to furnish broader knowledge of the multiple potentialities of some allergens and to emphasize the need to consider a more complete toxicologic picture of an industrial exposure.

The list of asthma-producing substances cited in Table 1 has been arbitrarily limited to exposures which can produce both allergic bronchial asthma and allergic contact dermatitis. The classic examples are ragweed hay fever-asthma and ragweed dermatitis. The water-soluble protein fraction of ragweed pollen causes the immediate response, i.e.,

hay fever or asthma, and the lipid fraction causes the

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