In 1898, Fabry1 reported a previously undescribed cutaneous disorder which has since been termed angiokeratoma corporis diffusum. Over the next few decades, dermatological periodicals contained reports of other examples of this condition. It slowly became apparent that this disorder was not limited to the integument, and that the cutaneous lesions merely represent the earliest and most easily demonstrable evidence of a sometimes fatal syndrome involving multiple organs.2,3 We wish to report an additional case of this syndrome and briefly review the characteristic manifestations.
The cutaneous lesions are the earliest aberration and have been present in all reported cases. They consist of minute macules and papules which may or may not have an overlying scale. The lesions are dark blue-red to purple in color and may appear black in older individuals. Slight, if any, change on diascopic pressure is characteristic. They are scattered over the entire body but tend
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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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