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Granuloma Faciale

WAINE C. JOHNSON, MC; ROBERT S. HIGDON, MC; ELSON B. HELWIG, M.D.
AMA Arch Derm. 1959;79(1):42-52. doi:10.1001/archderm.1959.01560130044005.
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Granuloma faciale is a dermatosis characterized clinically by elevated, usually asymptomatic, reddish-brown plaques on the face. The term granuloma faciale was first used by Pinkus,1 to define the lesions in a case he reported with Cobane and Straith.2 Formerly this disorder had been termed eosinophilic granuloma of the skin.

A study of 15 examples of granuloma faciale has been undertaken at the Armed Forces Institute of Pathology for the purpose of determining its natural history and relation to eosinophilic granulomas and of exploring its histogenesis.

Historical Review

Eosinophilic Granuloma of the Skin.— The term "eosinophilic granuloma of the skin" was first used in 1937, by Nanta and Gadrat,3 in reporting a patient with ulcerating lesions of the mouth and anus associated with tuberculosis. They also reviewed and included in this category a case reported by Freund4 and another by

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