Chromoblastomycosis, a common deep mycosis in Latin America, is notoriously resistant to therapy. In this monograph the author presents his experiences in the treatment of chromoblastomycosis with calciferol.
He acknowledges that calciferol has been previously recommended in the treatment of chromoblastomycosis by Castro Palomino and Armenteros in Cuba, Latapí in Mexico, and Bonilla in Costa Rica. His series of 20 carefully studied cases is the largest one reported, and allows comparison of the effects of the medication administered on different schedules. First, 600 units of calciferol were given daily. The lesions improved in four to six weeks, but signs of toxicity developed. Later, the medication was administered every second day; the most satisfactory results were obtained with weekly doses of calciferol, with a total of 15 to 25 doses. In all three schedules, the patients received 1 to 3 gm. of potassium or sodium iodide and routine local treatment (compresses,