Congenital Ichthyosiform Erythroderma. Presented by Drs. W. P. Lascheid, L. W. Potts, and W. E. Clendenning.
A 6-month-old Negro boy, presented at birth a generalized erythema and a marked thickening of the horny layer, which gave the skin a parchmentlike appearance. The skin of the face appeared taut, and there was a bilateral ectropion.
The baby was immediately transferred to Babies and Childrens Hospital, where he was placed in an incubator with high humidity, and Aquaphor was applied locally several times a day. Vitamin A was administered in high doses.
After about two weeks, the outer horny layer began to shed in various areas, leaving shield-like areas of keratin attached to fingers, toes, and several other areas on the extremities. These shields of keratin had to be cut from the fingers and toes to allow normal growth.
After several weeks in the constant humid atmosphere, the erythema