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July 1956, Vol 74, No. 1 >
Article | July 1956

Cellular Blue Nevus of Ota Followed for Twenty-Two Years

DAVID W. KERSTING, M.D.; MARCUS R. CARO, M.D.
AMA Arch Derm. 1956;74(1):59-62. doi:10.1001/archderm.1956.01550070061011.
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The nevus of Ota,1 first described in 1939 and named nevus fusco-caeruleus opthalmomaxillaris, has been recognized with increasing frequency in recent years, especially since 1952, when Ito and Yoshida reviewed its characteristics.2 It consists of a pigmented patch or group of macules of bluish or brownish color, involving the skin in the area of distribution of the first or second branch of the trigeminal nerve. It is generally unilateral and is frequently associated with melanosis of ocular or orbital structures. In the series of 26 patients reported by Tanino,3 it appeared shortly after birth in 17 instances, enlarging later in 6 of these (between the 14th and the 18th year of age). In the other nine patients it first appeared between the 10th and 18th year of life. Twenty of his patients were women and six were men. Melanosis of the

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