PAUTRIER and Woringer in 1932 described a large nodular swelling of the lymph nodes, that occurred in patients with erythrodermas, which they named lipomelanotic reticulosis. It was characterized by foci of reticulocytic proliferation in the basic lymph tissue of the lymph-node cortex. The cortical follicles were in part displaced, whereas the medullary follicles appeared unaffected. The remaining cortical follicles were mostly atrophic, occasionally retaining their original size; hypertrophic follicles rarely appeared. The proliferated reticulum cells were large and had a pale cytoplasm. Mitotic figures were conspicuously absent. Groups of such cells contained fat and melanin. Embedded haphazardly in this reticulum were eosinophiles, lymphocytes, plasma cells, and mast cells.
The authors interpreted their findings as an unspecific reaction of the basic lymph tissue to inflammatory processes involving large portions of the skin, and not as a nosologic entity. Similar observations were repeatedly reported (Laipply, Kocsard, and Obermayer, and Fox). The reporting
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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and
Association With Material Stature
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dhildhood mortality and growth failure data and their association with maternal
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